Synthesis, characterization and biological evaluation of a nanorod five‐coordinated Sn(IV) complex. Theoretical studies of (CH3)2Sn(O2PPh2)2

Dorosti, Niloufar; Mohammadpour, Hadis

doi:10.1002/aoc.4610

Cited by 6 publications

(1 citation statement)

References 61 publications

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“…In view of the above advantages, numerous organotin compounds have been synthesized and shown diverse structures including ladder, drum, cube, O‐capped cluster, butterfly cluster, extended cage, crown cluster and football cage . At the same time, the application of organotin compounds in catalytic chemistry, functional material, organic synthesis and biological activity have drawn growing interests . In particular, organotin compounds show a wide variety of biological activity which includes pesticides, antibacterial and anticancer .…”

Section: Introductionmentioning

confidence: 99%

Novel organotin (IV) complexes derived from 4,4′‐oxybisbenzoic acid: synthesis, structure, in vitro cytostatic activity and binding interaction with BSA

Wang

Zhang

et al. 2019

Applied Organom Chemis

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Six novel organotin (IV) complexes, [(Me 3 Sn) 2 (H 2 O) 2 L] (1), [(R 3 Sn) 2 L] n (R = Me 2, R = n-Bu 3), [(Ph 3 Sn) 2 L] (4), [Me 2 SnL] n (5), [(Me 2 Sn) 2 L(μ 3 -O)] n (6) have been designed and synthesized by the reactions of 4,4′-oxybisbenzoic acid (H 2 L) and triorganotin (IV) chloride or oxide. All the complexes have been characterized by elemental analysis, FT-IR, NMR, ESI-Mass, PXRD and X-ray crystallography.The single crystal diffraction reveals that complexes 1 and 4 represent dinuclear tin monomers. Complexes 2 and 3 display 2D network structure and 2D corrugated framework respectively, which both contain tetranuclear 36-membered macrocycles. Furthermore, 2D structures are linked into a 3D supramolecular structures through intermolecular C-H···π interactions. Complex 5 shows 1D infinite helical chain and further constructs 3D ladder supramolecular architecture through additional Sn···O and C-H···O intermolecular interactions. Complex 6 displays 1D infinite polymeric chain containing 28-membered macrocyclic ring. Preliminarily in vitro cytostatic activity studies on cervical carcinoma cell lines (HeLa) and hepatocellular carcinoma cell lines (HepG-2) by MTT assay for some complexes reveal that complexes 3 and 4 exhibit high cytostatic activity. Further, complexes 3 and 4 were selected to investigate interactions of bovine serum albumin (BSA) by fluorescence quenching spectra and synchronous fluorescence spectra, which indicates that the complexes could quench the intrinsic fluorescence of BSA in a static quenching process.

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Section: Introductionmentioning

confidence: 99%

Novel organotin (IV) complexes derived from 4,4′‐oxybisbenzoic acid: synthesis, structure, in vitro cytostatic activity and binding interaction with BSA

Wang

Zhang

et al. 2019

Applied Organom Chemis

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Nano‐ and micro‐structure tin (IV) complexes bearing 4‐pyridinecarbacylamidophosphate: Sonochemical synthesis, crystal structure, anti‐cholinesterase activity, and docking studies

Nikpour

Dorosti

Afshar

et al. 2020

Applied Organom Chemis

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Two di-and triorganotin (IV) complexes, Sn (CH 3) 2 Cl 2 (4-PCAPh) 2 (C 1) and Sn(C 6 H 5) 3 Cl(4-PCAPh) (C 2); {4-PCAPh = 4-NC 5 H 4 C(O)NHP(O) (C 6 H 12 N) 2 }, have been synthesized and characterized by elemental analysis, 1 H, 13 C, 31 P NMR and IR spectroscopy. The crystal structure of C 1 has been confirmed by X-ray crystallography, which reveals an octahedral geometry surrounding Sn (IV). Both ligands function in an all-trans conformation, with an N-ligated mode for 4-PCAPh. Also, the complexes were prepared at nano-(C 1) and micro-size (C 2) by the sonochemical process. The role of reaction solvent and the concentration of initial reactants on the size and morphology of particles were studied and the products were characterized by X-ray powder diffraction (XRPD) and scanning electron microscopy (SEM). The activities and mechanism of complexes C 1 , C 2 , C 1 , C 2 and their corresponding ligand (L) on cholinesterase (ChE) were evaluated using a modified Ellman's method and Lineweaver-Burk plots. Nanosheet C 1 showed the best activity against AChE and BChE with the IC 50 values being 73.08 ± 0.12 μM and 122.48 ± 0.69 μM, respectively, and the mixed-type mechanism. Molecular modeling simulation revealed the binding interaction template for Sn (CH 3) 2 Cl 2 (4-PCAPh) 2 with the ChE.

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Facile Preparation of Organometallic Nanorods from Various Ethynyl‐Substituted Molecules

et al. 2019

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A facile method to prepare one‐dimensional (1D) organometallic nanomaterials from various ethynyl‐substituted molecules is reported. The reactions of 3‐chloro‐1‐ethynylbenzene, p ‐ t Bu‐phenylacetylene and 4‐ethynylbiphenyl with Cu + ions in acetonitrile yield nanorod‐shaped copper acetylides (Cu−C≡C−R) crystals. In the case of linear alkynes, namely, propyne, 1‐pentyne and 1‐hexyne, it was found that using an aqueous ammonia/ethanol mixed solvent instead of acetonitrile is a better approach to obtain 1D nanostructures. This procedure also enables us to prepare functional 1D nanomaterials. We demonstrate the preparation of a paramagnetic nanorod from the organic radical p ‐ethynylphenyl nitronyl nitroxide, and fluorescent nanorods from 9‐ethynylphenanthrene and 2‐ethynyl‐9,9′‐spirobifluorene.

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Synthesis, characterization and biological evaluation of a nanorod five‐coordinated Sn(IV) complex. Theoretical studies of (CH₃)₂Sn(O₂PPh₂)₂

Cited by 6 publications

References 61 publications

Novel organotin (IV) complexes derived from 4,4′‐oxybisbenzoic acid: synthesis, structure, in vitro cytostatic activity and binding interaction with BSA

Novel organotin (IV) complexes derived from 4,4′‐oxybisbenzoic acid: synthesis, structure, in vitro cytostatic activity and binding interaction with BSA

Nano‐ and micro‐structure tin (IV) complexes bearing 4‐pyridinecarbacylamidophosphate: Sonochemical synthesis, crystal structure, anti‐cholinesterase activity, and docking studies

Facile Preparation of Organometallic Nanorods from Various Ethynyl‐Substituted Molecules

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