2006
DOI: 10.1016/j.jinorgbio.2005.09.012
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Synthesis, characterization and biological activity of lanthanum(III) complexes containing 2-methylene–1,10-phenanthroline units bridged by aliphatic diamines

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Cited by 138 publications
(33 citation statements)
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“…4), indicating that the CD spectrum was exhibiting a more positive feature instead of positive and negative peaks counteracting with each other. Some investigators believed that these type of changes in the CD spectra may be reflected due to a shift from a B-like DNA structure toward one with some contributions from an A-like conformation (Ivanov et al, 1973;Poklar et al, 1996;Li et al, 2006). While in the Tris buffer (pH 7.4), increasing the concentration of MIDBT in the ct-DNA solution (at R = 1.8, 3.6), the intensities of both positive and negative bands increased (Fig.…”
Section: Interaction Between Midbt and Ct-dna Measured By Circular DImentioning
confidence: 96%
“…4), indicating that the CD spectrum was exhibiting a more positive feature instead of positive and negative peaks counteracting with each other. Some investigators believed that these type of changes in the CD spectra may be reflected due to a shift from a B-like DNA structure toward one with some contributions from an A-like conformation (Ivanov et al, 1973;Poklar et al, 1996;Li et al, 2006). While in the Tris buffer (pH 7.4), increasing the concentration of MIDBT in the ct-DNA solution (at R = 1.8, 3.6), the intensities of both positive and negative bands increased (Fig.…”
Section: Interaction Between Midbt and Ct-dna Measured By Circular DImentioning
confidence: 96%
“…[53] To further confirm the interaction mode of the Cu(II) complex with DNA, a viscosity study was carried out (Fig. 4).…”
Section: Viscosity Measurementsmentioning
confidence: 99%
“…Hydrodynamic method, such as determination of viscosity, which is exquisitely sensitive to the change of length of DNA, may be the most effective means studying the binding mode of complexes to DNA in the absence of X-ray crystallographic or NMR structural data [42]. To further confirm the interaction mode of the Cu(II) complex with DNA, a viscosity study was carried out (Fig.…”
Section: Viscosity Studymentioning
confidence: 99%