Synthesis, characterization and antimicrobial activity of some nickel, cadmium and mercury complexes of 5-methyl pyrazole-3yl-N-(2′-methylthiophenyl) methyleneimine, (MPzOATA) ligand

Mandal, Susmita; Mondal, Monojit; Biswas, Jayanta Kumar; Cordes, David B.; Slawin, Alexandra M. Z.; Butcher, Ray J.; Saha, Manan; Saha, Nimai Chandra

doi:10.1016/j.molstruc.2017.09.015

Cited by 30 publications

(16 citation statements)

References 53 publications

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“…Although the present study does not show any direct experimental evidence about the mechanism of antibacterial activity of the Co and Ni complexes, it can be corroborated with our previous observation of membrane damage as inflicted by some Ni, Cd and Hg complexes against Gram positive (Bacillus subtilis 6633) and Gram negative (Proteus vulgaris OX19) bacterial strain [77].…”

Section: Antimicrobial Activitysupporting

confidence: 88%

Synthesis, characterization and antimicrobial activities of Co(III) and Ni(II) complexes with 5-methyl-3-formylpyrazole-N(4)-dihexylthiosemicarbazone (HMPzNHex2): X-ray crystallography and DFT calculations of [Co(MPzNHex2)2]ClO4·1.5H2O (I) and [Ni(HMPzNHex2)2]Cl2·2H2O (II)

Saha

Mondal

Ghosh

et al. 2018

Inorganica Chimica Acta

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A new pyrazole containing ligand, 5-methyl-3-formylpyrazole-N(4)-dihexylthiosemicarbazone (HMPzNHex2), and a host of its cobalt(III) and nickel(II) complexes, [Co(MPzNHex2)2]X·mH2O and [Ni(HMPzNHex2)2]X2·nH2O (X= Cl, Br, ClO4, BF4 and NO3; m = 0 for Cl, Br, BF4 & NO3 and 1.5 for ClO4; n = 0 for Br, ClO4, BF4 & NO3 and 2 for Cl), respectively, have been synthesized and characterized by elemental analyses, magnetic measurements (polycrystalline state), 1 H NMR (for the ligand and its Co(III) complexes), electronic and IR spectral parameters. All the reported Co (III) and Ni(II) complexes are cationic in nature and behaving as 1:1 and 1:2 electrolytes, respectively, in MeOH. Electronic spectral data of the complexes categorize them as having distorted octahedral coordination geometry. IR spectral features (4000-/450 cm -1 ) specify a monodeprotonated / neutral tridentate (NNS) function of the ligand, HMPzNHex2 coordinating to the Co(III) / Ni(II) via the pyrazolyl (tertiary) ring nitrogen, azomethine nitrogen and thiolato / thioketo sulfur atom. 1 H NMR spectral data (in CDCl3 at 400 MHz) for the primary ligand and those of its Co(III) complexes are in agreement with the proposition of bonding sites evidenced from IR data. The single crystal x-ray data of I (C2/c (#15); monoclinic) and II (P-1 (#2); triclinic) have confirmed a CoN4S2 and a NiN4S2 octahedral coordination, respectively. The pair of monoprotic / neutral coordinating ligands

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Section: Antimicrobial Activitysupporting

confidence: 88%

Synthesis, characterization and antimicrobial activities of Co(III) and Ni(II) complexes with 5-methyl-3-formylpyrazole-N(4)-dihexylthiosemicarbazone (HMPzNHex2): X-ray crystallography and DFT calculations of [Co(MPzNHex2)2]ClO4·1.5H2O (I) and [Ni(HMPzNHex2)2]Cl2·2H2O (II)

Saha

Mondal

Ghosh

et al. 2018

Inorganica Chimica Acta

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“…Co(II), Ni(II), and Zn(II) complexes did not show such signicant antimicrobial activity. 37 Similar discrepancies in the antimicrobial activity were observed by Mandal et al 37 who described a strong biostatic effect of cadmium and mercury complexes of 5-methyl pyrazole-3yl-N-(20-methylthiophenyl) methyleneimine, (MPzOATA) ligand, against some Gram-positive and Gram-negative bacteria, while nickel complexes with the same ligands (…”

Section: Crystal Structuresmentioning

confidence: 53%

Anticancer and antimicrobial properties of novel η⁶-p-cymene ruthenium(ii) complexes containing a N,S-type ligand, their structural and theoretical characterization

et al. 2019

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“…Recently, Mondal et al reported the syntheses and antimicrobial activity of some Ni(II), Cd(II) and Hg(II) complexes of a pyrazole containing Schiff base ligands. The results showed that the complex 207 demonstrated highest antimicrobial agents against both Gram positive and Gram negative bacteria [ 111 ]. A series of isoxazolyl thiazolyl pyrazoles were synthesized by Mor et al and evaluated in vitro for antimicrobial activity.…”

Section: Pharmacological Activitiesmentioning

confidence: 99%

Synthesis and Pharmacological Activities of Pyrazole Derivatives: A Review

et al. 2018

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Pyrazole and its derivatives are considered a pharmacologically important active scaffold that possesses almost all types of pharmacological activities. The presence of this nucleus in pharmacological agents of diverse therapeutic categories such as celecoxib, a potent anti-inflammatory, the antipsychotic CDPPB, the anti-obesity drug rimonabant, difenamizole, an analgesic, betazole, a H2-receptor agonist and the antidepressant agent fezolamide have proved the pharmacological potential of the pyrazole moiety. Owing to this diversity in the biological field, this nucleus has attracted the attention of many researchers to study its skeleton chemically and biologically. This review highlights the different synthesis methods and the pharmacological properties of pyrazole derivatives. Studies on the synthesis and biological activity of pyrazole derivatives developed by many scientists around the globe are reported.

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Synthesis, characterization and antimicrobial activity of some nickel, cadmium and mercury complexes of 5-methyl pyrazole-3yl-N-(2′-methylthiophenyl) methyleneimine, (MPzOATA) ligand

Abstract: , characterization and antimicrobial activity of some nickel, cadmium and mercury complexes of 5-methyl-3yl-N-(2´-methylthiophenyl)methyleneimine, (MP z OATA) ligand

Cited by 30 publications

References 53 publications

Synthesis, characterization and antimicrobial activities of Co(III) and Ni(II) complexes with 5-methyl-3-formylpyrazole-N(4)-dihexylthiosemicarbazone (HMPzNHex2): X-ray crystallography and DFT calculations of [Co(MPzNHex2)2]ClO4·1.5H2O (I) and [Ni(HMPzNHex2)2]Cl2·2H2O (II)

Synthesis, characterization and antimicrobial activities of Co(III) and Ni(II) complexes with 5-methyl-3-formylpyrazole-N(4)-dihexylthiosemicarbazone (HMPzNHex2): X-ray crystallography and DFT calculations of [Co(MPzNHex2)2]ClO4·1.5H2O (I) and [Ni(HMPzNHex2)2]Cl2·2H2O (II)

Anticancer and antimicrobial properties of novel η⁶-p-cymene ruthenium(ii) complexes containing a N,S-type ligand, their structural and theoretical characterization

Synthesis and Pharmacological Activities of Pyrazole Derivatives: A Review

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Synthesis, characterization and antimicrobial activity of some nickel, cadmium and mercury complexes of 5-methyl pyrazole-3yl-N-(2′-methylthiophenyl) methyleneimine, (MPzOATA) ligand

Abstract: , characterization and antimicrobial activity of some nickel, cadmium and mercury complexes of 5-methyl-3yl-N-(2´-methylthiophenyl)methyleneimine, (MP z OATA) ligand

Cited by 30 publications

References 53 publications

Synthesis, characterization and antimicrobial activities of Co(III) and Ni(II) complexes with 5-methyl-3-formylpyrazole-N(4)-dihexylthiosemicarbazone (HMPzNHex2): X-ray crystallography and DFT calculations of [Co(MPzNHex2)2]ClO4·1.5H2O (I) and [Ni(HMPzNHex2)2]Cl2·2H2O (II)

Synthesis, characterization and antimicrobial activities of Co(III) and Ni(II) complexes with 5-methyl-3-formylpyrazole-N(4)-dihexylthiosemicarbazone (HMPzNHex2): X-ray crystallography and DFT calculations of [Co(MPzNHex2)2]ClO4·1.5H2O (I) and [Ni(HMPzNHex2)2]Cl2·2H2O (II)

Anticancer and antimicrobial properties of novel η6-p-cymene ruthenium(ii) complexes containing a N,S-type ligand, their structural and theoretical characterization

Synthesis and Pharmacological Activities of Pyrazole Derivatives: A Review

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Anticancer and antimicrobial properties of novel η⁶-p-cymene ruthenium(ii) complexes containing a N,S-type ligand, their structural and theoretical characterization