Synthesis, Characterization and antibacterial activity of Magnesium Oxide (MgO) nanoparticles.

Almontasser, Asma; Parveen, Azra; Azam, Ameer

doi:10.1088/1757-899x/577/1/012051

Cited by 58 publications

(33 citation statements)

References 17 publications

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“…87-0653), where significant peaks can be assigned close to the 2

angle values of 36.8, 42.9, 62.2, 74.6, and 78.6°, which can be indexed to the lattice planes (111), (200), (220), (311), and (222), respectively. The typical pattern is shown in Figure 3 a, whereby similar results have been widely published [ 26 , 27 , 28 , 29 , 30 ]. The Scherrer [ 31 ] equation is most commonly used in the literature to determine the crystallite size of synthesized nanostructures from XRD results.…”

Section: Introductionsupporting

confidence: 82%

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Synthesis, Properties, and Selected Technical Applications of Magnesium Oxide Nanoparticles: A Review

Hornak

2021

IJMS

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In the last few decades, there has been a trend involving the use of nanoscale fillers in a variety of applications. Significant improvements have been achieved in the areas of their preparation and further applications (e.g., in industry, agriculture, and medicine). One of these promising materials is magnesium oxide (MgO), the unique properties of which make it a suitable candidate for use in a wide range of applications. Generally, MgO is a white, hygroscopic solid mineral, and its lattice consists of Mg2+ ions and O2− ions. Nanostructured MgO can be prepared through different chemical (bottom-up approach) or physical (top-down approach) routes. The required resultant properties (e.g., bandgap, crystallite size, and shape) can be achieved depending on the reaction conditions, basic starting materials, or their concentrations. In addition to its unique material properties, MgO is also potentially of interest due to its nontoxicity and environmental friendliness, which allow it to be widely used in medicine and biotechnological applications.

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“…87-0653), where significant peaks can be assigned close to the 2

Section: Introductionsupporting

confidence: 82%

“… Structural characterization of magnesium oxide: ( a ) XRD pattern and ( b ) FTIR spectra (redrawn and adapted from the results presented in [ 26 , 27 , 28 , 29 , 30 , 37 , 38 , 39 , 40 ]). …”

Section: Introductionmentioning

confidence: 99%

Synthesis, Properties, and Selected Technical Applications of Magnesium Oxide Nanoparticles: A Review

Hornak

2021

IJMS

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“…Nanotechnology is a rapidly expanding field which involves the synthesis and characterization of noble metals such as silver, gold, and platinum as nanoparticles. The importance of nanotechnology relies on its wide applications in drug delivery, bioengineering, textile engineering, biological labeling, biotechnology, catalysis, water treatment and the detection of genetic disorders [1][2][3][4]. Nanoparticles are of maximum size of 100 nm showing different chemical, optical, mechanical, electronic and magnetic properties than larger particles due to the variation in specific characteristics such as shape, size and atomic distribution [1,5].…”

Section: Introductionmentioning

confidence: 99%

The synergistic effect of biosynthesized silver nanoparticles from a combined extract of parsley, corn silk, and gum arabic: in vivo antioxidant, anti-inflammatory and antimicrobial activities

Helmy

El-Shazly

Seleem

et al. 2020

Mater. Res. Express

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Microbial resistance, oxidative stress, and inflammatory conditions are among the leading causes of death worldwide. In the current work, silver nanoparticles (AgNPs) were biosynthesized using the aqueous extracts of parsley, corn silk (CS), gum Arabic (GA) or combination of the three extracts. The formed nanoparticles were characterized using three techniques including transmission electron microscopy (TEM), UV-visible spectrophotometer and Fourier-transform infrared spectroscopy (FTIR). The antioxidant, anti-inflammatory, and antimicrobial activities were tested for the formed nanoparticles, the aqueous extracts of each of the three plants and their combination. Oxidative stress was induced by alloxan which promoted the development of diabetes mellitus in rats. Inflammation was induced by injecting carrageenan in rats' paws. Pathogenic microorganisms causing serious urinary tract infection (UTI) were selected for the antimicrobial assay. All aqueous extracts and the biosynthesized AgNPs showed variable degrees of antioxidant, anti-inflammatory and antimicrobial activities, however, the AgNPs biosynthesized by the combination of the three aqueous extracts was the most effective one. LC/MS was done to identify the compounds present in the crude extracts that may be responsible for the observed biological activities. LC/MS resulted in the identification of 13 compounds. Docking experiments on COX-1 (cyclooxygenase-1) and COX-2 (cyclooxygenase-2) were performed to determine the compounds responsible for the antiinflammatory activity of the extracts. The results showed that silver nanoparticles synthesized by the combination of the three aqueous extracts are considered promising candidates for the development of antioxidant, anti-inflammatory and antimicrobial agents. photochemical [10], electrochemical [7, 11], reverse micelle [12], thermal decomposition [13], radiation [7,14] and microwave-assisted [7] methods. Most of these methods require the use of hazardous chemicals and high energy for the preparation of nanoparticles. Biological synthesis of nanoparticles involves the use of natural materials such as plants, bacteria, fungi [1,5,15]. The use of plants for the synthesis of nanoparticles have an advantage over other biological methods as it does not involve the use of cell culture, and does not need longer incubation time required for the reduction of metal ions [16,17]. Plants are known to contain various secondary metabolites such as alkaloids, terpenoids, flavonoids and tannins which provide suitable reducing and surface agents for the nanoparticle synthesis and stabilization. Biopolymers such as cellulose, chitosan, alginate, dextran and tree gums are another family of natural sources which were used for the reduction and stabilization of nanoparticles [17,18].Recently, pathogenic bacteria and fungi such as Staphylococci spp., Enterococci spp., Klebsiella pneumoniae, and Pseudomonas spp. demonstrated resistance to commercially available antimicrobial agents at an increasing rate and has become a global thr...

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“…22 Due to increasing antibiotic resistance in E.faecalis strains the use of alternative antibacterial agents such as metallic nanoparticles have prompted a renewed interest. 23 In the present study nano-Mgo solution is used as an endodontic irrigant. Nano-Mgo has the advantages of non-toxicity, pepared from readily avaliable resources, economical and therefore has considerable potential as a bactericidal material.…”

Section: Discussionmentioning

confidence: 99%

Ex-Vivo evaluation of Nano-MgO in the elimination of Endodontic pathogen- E. faecalis

Bhardwaj¹,

Shorey²,

Sidhu³

et al. 2021

IJCE

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Magnesium oxide (MgO) nanoparticles due to their antimicrobial properties and ability to survive under harsh conditions have become an area of interest in the field of biomedical sciences. The aim of the study was to evaluate antimicrobial efficacy of Nano-MgO in the elimination of endodontic pathogen . Minimum inhibitory concentration (MIC) of Nano-MgO and sodium hypochlorite against was calculated using broth dilution method. The antibacterial efficacy of Nano-MgO in elimination of the pathogens was seen using an ex-vivo model of decoronated teeth which were experimentally infected. The antibiofilm activity of the tested antimicrobial agents on biofilms was determined quantitatively by counting the colonies on Mueller-Hinton agar plates and by evaluation under scanning electron microscopy (SEM). The data analysis was done using one way ANOVA and the intergroup comparison by student –t test. MIC concentration of Nano-MgO was observed at 10mg/ml for . Mean values of colony forming unit (CFU) count was maximum for normal saline, followed by Nano-MgO and sodium hypochlorite with a significant difference between all the three groups. The results of the study reveal that Nano-MgO has the potential to be used as an alternative irrigating solution in endodontic therapy.

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Synthesis, Characterization and antibacterial activity of Magnesium Oxide (MgO) nanoparticles.

Cited by 58 publications

References 17 publications

Synthesis, Properties, and Selected Technical Applications of Magnesium Oxide Nanoparticles: A Review

Synthesis, Properties, and Selected Technical Applications of Magnesium Oxide Nanoparticles: A Review

The synergistic effect of biosynthesized silver nanoparticles from a combined extract of parsley, corn silk, and gum arabic: in vivo antioxidant, anti-inflammatory and antimicrobial activities

Ex-Vivo evaluation of Nano-MgO in the elimination of Endodontic pathogen- E. faecalis

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