Synthesis, characterization and anti-microbial activity of poly(ethylene oxamide- N,N ′-disuccinate) and its polymer metal complexes

Abstract

Poly(ethylene oxamide-N,N 0 -disuccinate), abbreviated as (PEODS), has been synthesized by condensation of oxamide-N,N 0 -disuccinic acid and 1,2-ethylene glycol. Coordination polymers were synthesized by the reaction of (PEODS) with hydrated acetates of Mn(II), Co(II), Ni(II), Cu(II) and Zn(II). The resulting polyester-metal complexes were characterized by elemental analysis, UV-Visible, FT-IR, 1 H-NMR, ESR spectroscopy and magnetic susceptibilities. Thermal behavior of all the synthesized compounds revealed that polymer metal complexes are more stable than the polymeric ligand. In addition all the synthesized polymers were screened for anti-bacterial activity against B. subtelillisr, B. megaterium, S. aureus, E. coli, S. typhi, P. aeruginosa, S. boydii and for antifungal activity against C. albicans, T. species, A. flavus, A. niger, F. species, M. species, and P. species by agar well diffusion methods. All the polymers showed good anti-bacterial and anti-fungal activity, which increased on coordination with the metal ions.

Synthesis, Spectral, Morphology, Thermal Degradation Kinetics and Antibacterial Studies of Terpolymer Metal Complexes

“…Anti-microbial activity of poly(ethylene oxamide-N,N 0 -disuccinate) and its polymer metal complexes was tested against few bacterial and fungal strains. All the polymers showed good anti-bacterial and anti-fungal activity which increased on coordination with the metal ions [15]. Anti-microbial activities of 6-coordinate antimony(III) complexes with tridentate 2-acetylpyridine thiosemicarbazone, bis(thiosemicarbazone) and semi carbazone ligands were reported [16].…”

Antimicrobial study of polymeric ligands derived from 2, 4-dihydroxy acetophenone and their lanthanide (III) polychelates

“…Ahamad et al [5] have synthesized poly(ethylene oxamide-N,N'-disuccinate) (PEODS) by condensation of oxamide-N,N'-disuccinic acid and ethylene glycol. Their coordination polymers were synthesized by the reaction of PEODS with hydrated acetates of Mn(II), Co(II), Ni(II), Cu (II) and Zn(II).…”

Syntheses, spectroscopic and magnetic properties of polystyrene-anchored coordination compounds of thiazolidinone

“…The ν 2 /ν 1 value is 1.73 and lies in the usual range: 1.60-1.82 reported for majority of octahedral Ni(II) compounds [31]. The spectral parameters are: Dq = 932 cm T 1g (G), 6 A 1g → 4 T 2g (G) and 6 A 1g → 4 A 1g (G) transitions respectively, in an octahedral symmetry [30].…”

“…Heterogenization or immobilization of active metal complexes on polymeric supports has evolved as a promising strategy for combining the advantages of homogeneous and heterogeneous catalysts due to their easy isolation from the products by filtration and the possibility of recycling them or continuous operation in a reactor [2]. A structural study of polymer-anchored compounds seems useful in view of their numerous applications in analytical chemistry [3], metal ion removal [4], immobilization of enzymes [5], antimicrobial activities [6], as catalysts [7][8], as solid supports [9], as substrate carriers [10] and a s ion-exchanger [11], etc.…”