Synthesis, characterisation and antimicrobial activities of vic-dioxime derivatives containing heteroaromatic hydrazone groups and their metal complexes

Bıyık, Halil; Babahan, İlknur; Çoban, Esin Poyrazoğlu

doi:10.14456/mijst.2013.2

Cited by 3 publications

(1 citation statement)

References 43 publications

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“…Compound 41 , which contains a methylfuryl moiety instead of a methylphenyl moiety, demonstrated less antifungal activity against S. cerevisiae (MIC = 16 µg/mL) than 40 , along with antibacterial activity against B. cereus (MIC = 8 µg/mL) and Streptococcus pneumoniae (MIC = 16 µg/mL). Derivative 42 , which possesses a pyridine ring, was selective to the Candida tropicalis fungal strain (MIC = 8 µg/mL) [ 39 ].…”

Section: Resultsmentioning

confidence: 99%

A Review of the Biological Activity of Amidrazone Derivatives

et al. 2022

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Amidrazones are widely used in chemical synthesis, industry and agriculture. We compiled some of the most important findings on the biological activities of amidrazones described in the years 2010–2022. The data were obtained using the ScienceDirect, Reaxys and Google Scholar search engines with keywords (amidrazone, carbohydrazonamide, carboximidohydrazide, aminoguanidine) and structure strategies. Compounds with significant biological activities were included in the review. The described structures derived from amidrazones include: amidrazone derivatives; aminoguanidine derivatives; complexes obtained using amidrazones as ligands; and some cyclic compounds obtained from amidrazones and/or containing an amidrazone moiety in their structures. This review includes chapters based on compound activities, including: tuberculostatic, antibacterial, antifungal, antiparasitic, antiviral, anti-inflammatory, cytoprotective, and antitumor compounds, as well as furin and acetylocholinesterase inhibitors. Detailed information on the compounds tested in vivo, along the mechanisms of action and toxicity of the selected amidrazone derivatives, are described. We describe examples of compounds that have a chance of becoming drugs due to promising preclinical or clinical research, as well as old drugs with new therapeutic targets (repositioning) which have the potential to be used in the treatment of other diseases. The described examples prove that amidrazone derivatives are a potential source of new therapeutic substances and deserve further research.

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Section: Resultsmentioning

confidence: 99%

A Review of the Biological Activity of Amidrazone Derivatives

et al. 2022

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Synthesis and Biological Properties of the Novel Coordination Compound with Rhodanine-3-Acetic Acid

et al. 2019

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A review exploring biological activities of hydrazones

et al. 2014

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The development of novel compounds, hydrazones has shown that they possess a wide variety of biological activities viz. antimicrobial, anticonvulsant, antidepressant, anti-inflammatory, analgesic, antiplatelet, antimalarial, anticancer, antifungal, antitubercular, antiviral, cardio protective etc., Hydrazones/azomethines/imines possess-NHN = CH- and constitute an important class of compounds for new drug development. A number of researchers have synthesized and evaluated the biological activities of hydrazones. This review aims at highlighting the diverse biological activities of hydrazones.

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Synthesis, characterisation and antimicrobial activities of vic-dioxime derivatives containing heteroaromatic hydrazone groups and their metal complexes

Cited by 3 publications

References 43 publications

A Review of the Biological Activity of Amidrazone Derivatives

A Review of the Biological Activity of Amidrazone Derivatives

Synthesis and Biological Properties of the Novel Coordination Compound with Rhodanine-3-Acetic Acid

A review exploring biological activities of hydrazones

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