“…Sulfonamide derivatives has been well known for their antitumor [2], anti-diabetic [3], anti-malarial [4], antimicrobial [5][6], anti-inflammatory [7], antioxidant [8], COX inhibitors [9], lipoxygenase inhibitors [10], alzheimer ' s disease [11], etc. Many literature survey revealed that 1,3,4-oxadiazole possess diverse pharmacological activities such as anticancer [12][13][14], antimicrobial [15][16][17][18], anti-HIV [19], antiproliferative [20], antiviral [21], anti-inflammatory [22][23], anticonvulsant [24]. Some of 2,5-disubstituted 1,3,4oxadiazole based entities have emerged as most potent antimicrobial activities.…”