Synthesis, bioinformatics and biological evaluation of novel α-aminophosphonates as antibacterial agents: DFT, molecular docking and ADME/T studies

Synthesis of 6H-Chromeno[4,3-b]quinolin-7-ylphosphonates through Three Component Phosphonylation of Coumarin Carbaldehyde and Their Antimicrobial and Photophysical Properties

“…Among these, aminophosphonates are of the most intensively investigated in interdisciplinary fields of science with a wide range of applications in industrial, agricultural, and medicinal chemistry fields due to their biological and physical properties as well as their use as synthetic intermediates (Figure ). , Recently, aminophosphonate derivatives embedded in heterocyclic frameworks have shown interesting biological and physical activities. − It seems that the presence of heterocyclic parts in the molecular structure of the aminophosphonates has a significant effect on their biological and optical properties. On the other hand, construction of small molecules including phosphonate groups at cyclic amines is of particular significance in organic chemistry …”

Experimental synthesis, biological evaluation, theoretical investigations of some novel benzoxazolinone based Schiff under eco-environmental conditions as potential antioxidant agents

“…Generally, catalyst-free and solvent-free processes can be achieved using microwave irradiation. [38,39] In continuation of our field of study on the synthesis and biological evaluation of organo-phosphorus and -sulfur compounds, [40][41][42][43] we describe here a simplified three-component one-pot synthesis of sulfamide-containing bisphosphonates derivatives under microwave irradiation. This method respects remarkable principles of green chemistry; atom economy, design for energy efficiency, safety and environment friendly without using any catalyst or solvent, thus reduce chemical waste and reaction time.…”

One‐Pot Microwave‐Assisted Synthesis, in Vitro Anti‐inflammatory Evaluation and Computer‐Aided Molecular Design of Novel Sulfamide‐Containing Bisphosphonates Derivatives

“…Generally, catalyst-free and solvent-free processes can be achieved using microwave irradiation. [38,39] In continuation of our field of study on the synthesis and biological evaluation of organo-phosphorus and -sulfur compounds, [40][41][42][43] we describe here a simplified three-component one-pot synthesis of sulfamide-containing bisphosphonates derivatives under microwave irradiation. This method respects remarkable principles of green chemistry; atom economy, design for energy efficiency, safety and environment friendly without using any catalyst or solvent, thus reduce chemical waste and reaction time.…”