2020 DOI: 10.20944/preprints202008.0438.v1 View full text Preprint
|
|
Share
Nurul Zawani Alias, Muhd Hanis Md Idris, Nurhafizoh Abdul Somat, Norwaziah Mahmud, Sharizal Hasan, Lam Kok Wai, Azwan Mat Lazim, Nurul Izzaty Hassan

Abstract: Inhibition of acetylcholinesterase (AChE) enzyme is a known procedure to treat severe Alzheimer's disease through increasing the acetylcholine level in the brain and thus slowing down the progression of Alzheimer's symptoms. The approved medications are only considered as palliative and addressed some reported deficiencies. Therefore, the demand for safe and effective compounds is substantially increasing. A newly series of coumaryl 1,3-selenazoles derivatives was synthesized in four steps. Then, their antioxi…

expand abstract