Synthesis, antimicrobial activity and molecular simulation of thiourea derivatives containing 6-carboalkoxybenzo[d]thiazole and d-glucose moieties

Abstract

Several substituted thiourea derivatives containing 6-carboalkoxybenzothiazole and D-glucose moieties 4a-i have been synthesized from reaction of corresponding alkyl 2-aminobenzothiazole-6-carboxyl 2a-i with 2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl isothiocyanate. Their antimicrobial activity against antibacterial (including Gram-positive,...