Synthesis, antibacterial activities and molecular docking studies of Schiff bases derived from N-(2/4-benzaldehyde-amino) phenyl-N′-phenyl-thiourea

Crystal structure of 2[(4-fluorophenylimino)methyl]-4,6-diiodophenol, C13H8FI2NO

“…Schiff bases have been extensively studied for their biological activities [1][2][3]. In addition, Schiff bases have also been widely used as ligands in the preparation of complexes [4][5][6].…”

Design, synthesis, and antibacterial evaluation of new Schiff’s base derivatives bearing nitroimidazole and pyrazole nuclei as potent E. coli FabH inhibitors

“…The results of these predictions have provided a therapeutic pathway to develop new effective biologically active Schiff's base derivatives. Many researchers have studied the synthesis, characterization, and structureactivity relationship (SAR) of Schiff's bases, and some were reported to have antibacterial activities [17]. Further, Kim et al reported the YKAs3003, a Schiff's base condensed by 4-hydroxy salicylaldehyde and cyclohexanamine, as a potent inhibitor of Escherichia coli (E. coli) FabH with antimicrobial activity [18].…”

Synthesis, structures and antibacterial activities of benzoylthiourea derivatives and their complexes with cobalt

“…Thiourea, benzene sulfonyl urea, dihydropyrimidine thiones, thiazines and their related analogues have become the focus of interest recently on account of their pharmacological activities [25][26][27][28][29][30][31][32]. Some compounds of urea and thiourea have shown bactericidal, fungicidal and herbicidal activities [33][34][35][36][37][38][39][40]. They can be used not only in the control of animal pathogenic bacteria but also they have been shown to possess antitubercular, antifungal, antithyroid, insecticidal, anthelmintic and rodenticidal properties [31][32][33][34][35][36][37][38][39][40].…”