“…5 Coumarin and its derivatives are important oxygen containing heterocycles which are found in natural products. Over the past decades, coumarins have attracted great attention because of their interesting biological and pharmacological activities such as anticoagulant, 7 antiinflammatory, 8,9 antioxidant, 10 antiviral, 11 antimicrobial, 12,13 antidepressants, 14 and anti-HIV effects. [15][16][17] Also, they are promising compounds due to their low toxicity, little drug resistance, less side effects, high bioavailability, and ease of chemical synthesis.…”