Synthesis and X-ray structural characterisation of the tetramethylene oxonium derivative of the hydrodecaborate anion. A versatile route for derivative chemistry of [B10H10]2−

Reactions of the [B10H10]2− anion with nucleophiles in the presence of halides of group IIIA and IVB elements

“…13 C NMR { 1 H} (CD 3 CN), δ, ppm: 58.2 (СН 2 (β)), 82.9 (СН 2 (α)). 11 B NMR (CН 3 CN, BF 3 ⋅ O 2 Et as the standard), δ, ppm: 6.2 (s, B(2)), -0.9 (d, B(10)), -8.1 (d, B(1)), ⎯23.4, -25.1 (B (3,5,6,9)), -31.9 (d, B (4,7,8) Tetraphenylphosphonium 2 (1 tetrahydrofuranium) nonahydro closo decaborate, (Ph 4 P)[B 10 H 9 OC 4 H 8 ], (Ph 4 P) [3], was prepared by the reaction of (Ph 4 P) 2 [1] with tetrahydrofuran in the presence of 2 equiv. of Lewis acid.…”

“…13 C NMR { 1 H} (CD 3 CN), δ, ppm: 36.44 (СН 2 (β)), 54.64 (СН 2 (α)). Tetraphenylphosphonium 2 (ethylideneammonio) nonahydro closo decaborate, (Ph 4 P)[B 10 H 9 NCCH 3 ], (Ph 4 P) [6], was prepared by the reaction of (Ph 4 P) 2 [1] with acetonitrile in the presence of 2 equiv. of Lewis acid.…”

Polyhedral Boranes for Medical Applications: Current Status and Perspectives

“…The sodium salt of the parent closo-decaborate, Na 2 [B 10 H 10 ] (GB-10), is approved for human use by the US Food and Drug Administration. However, the chemistry of closo-decaborate is much less studied than that of closo-dodecaborate, and despite new research activity in this field, [16][17][18] to the best of our knowledge only two reports on the medical application of closo-decaborate derivatives have appeared for the last years. [19] The carba-closo-dodecaborate anion, [ 2-: the good solubility in water as the sodium salt and the presence of a carbon atom available for functionalization by standard methods of organic chemistry.…”

Synthesis of carbocation salts of boron cluster anions [B10H10]2− and [B12H12]2−

“…Such complexes are intermediates of EINS reactions and can be isolated in some cases in a free state [5][6][7]. However, no complexes derived from closo borate anions and carbocations were obtained until now as individual compounds.…”