Synthesis and fungicidal activity of novel pyrazole derivatives containing 5-Phenyl-2-Furan

A Compendium of the Most Promising Synthesized Organic Compounds against Several Fusarium oxysporum Species: Synthesis, Antifungal Activity, and Perspectives

“…Ahmed et al (2019) designed and synthesized a series of new pyrazole derivatives containing 5-phenyl-2-furan by amidation reaction between furan carboxylic acid derivatives and 1 H -pyrazole assisted by thionyl chloride with good yields ( Scheme 70 ). The most active compounds against FOX were 128 and 129 ; however, all the evaluated compounds showed lower activity than pentiopyrad, pyrimorph, and hymexazole [ 146 ]. Recently, Tiwari et al (2018) reported on the synthesis of a new series of derivatives of 4-[(4,5-diphenyl-2-phenyl/2-substituted heteryl)-1 H -imidazol-1-yl] pyrimidine-2(1 H )—one using a protocol that employed a cyclo condensation in the ionic liquid triethylammonium hydrogen sulfate [Et 3 NH] [HSO 4 ].…”

Syntheses, structures, in vitro cytostatic activity and antifungal activity evaluation of four diorganotin(iv) complexes based on norfloxacin and levofloxacin

“…Scanning electron microscopy (SEM) of Physalospora piricola treated with complex 2 was carried out. [30][31][32] Physalospora piricola hyphae were incubated in PDB (potato dextrose broth) medium for 72 h at 25 1C (150 rpm). The hyphae were harvested by centrifugation (4500 rpm, 5 min), and then complex 2 was added at the maximum inhibitory concentration of 50 mg mL À1 for treatment for 24 h. The blank control group was the PDB medium containing hyphae without complexes.…”

Benefits and applications of microwave-assisted synthesis of nitrogen containing heterocycles in medicinal chemistry

“…Certain variations of this compound showed high antifungal activity, specically toward P. infestans. 76 Pyrazole has also been used as a privileged scaffold for monoamine oxidase inhibitors, protein B-Raf inhibitors, DNA gyrase inhibitors, anti-hepatotoxicity agents, antileishmanial agents, analgesics, cyclin-dependent kinase inhibitors, IRAK4 inhibitors, antibacterial and antifungal activities, antioxidants and 5areductase inhibitors (Fig. 8).…”