Synthesis and evaluation of antioxidant and antimicrobial activities of Schiff base tin (II) complexes

Neelofar, Neelofar; Ali, Nauman; Ahmad, Shabir; El-Salam, N. M. Abd; Ullah, Riaz; Nawaz, Robila; Ahmad, Sohail

doi:10.4314/tjpr.v15i12.22

Cited by 11 publications

(5 citation statements)

References 11 publications

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“…The tin complexes of different compounds are potential complexes in the management of leishmaniasis, free radicals scavenging, DNA interaction and as antimicrobial (Raychaudhury et al, 2005 ; Raza et al, 2016 ). The complexes of antimony have also a vital role in antimicrobial, antioxidant and anticancer activities (Viswanathan et al, 2000 ; Ejidike and Ajibade, 2015 ; Neelofar et al, 2016 ). The zinc complexes of several different classes of compounds have been extensively studied as an antioxidant and antimicrobial agents (Howard et al, 1973 ; Wang et al, 2006 ; Kadhum et al, 2011 ; Zaidi et al, 2012 ; Sheikh et al, 2013 ; Tarushi et al, 2013 ; Urquiza et al, 2013 ; Wu et al, 2013 ; Montazerozohori et al, 2014 ; Ebrahimiasl et al, 2015 ).…”

Section: Resultsmentioning

confidence: 99%

Ursolic Acid Hydrazide Based Organometallic Complexes: Synthesis, Characterization, Antibacterial, Antioxidant, and Docking Studies

et al. 2018

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In thecurrent research work,eleven metal complexes were synthesized from the hydrazide derivative of ursolic acid. Metal complexes of tin, antimony and iron were synthesized and characterized by FT-IR and NMR spectroscopy. The antibacterial and antioxidant activities were performed for these complexes, which revealed that the metal complexes synthesized are more potent than their parent compounds. We observed that antioxidant activity showed by triphenyltin complex was significant and least activity have been shown by antimony trichloride complex. The synthesized metal complexes were then evaluated against two Gram-negative and two Gram-positive bacterial strains. Triphenyl tin complex emerged as potent antibacterial agent with MIC value of 8 μg/ml each against Shigellaspp, Salmonella typhi and Staphylococcus aureus. While, the MIC value against Streptococcus pneumoniae is 4 μg/ml. Computational docking studies were carried out on molecular targets to interpret the results of antioxidant and antibacterial activities. Based on the results, it may be inferred that the metal complexes of ursolic acid are more active as compared to the parent drug and may be proved for some other pharmacological potential by further analysis.

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Section: Resultsmentioning

confidence: 99%

Ursolic Acid Hydrazide Based Organometallic Complexes: Synthesis, Characterization, Antibacterial, Antioxidant, and Docking Studies

et al. 2018

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“…The Tin (II) chloride complexes with many Schiff base derivative of 2-Hydroxy-1-naphthaldehyde (HN) have been synthesized and screened for their antioxidant activities by DPPH technique. All the complexes showed great antioxidant activities and better antioxidant activities than their corresponding ligands [86][87][88]. Schiff bases of Sulphanilamide and its complexes with elements like Cu, Zn and Cd metals have been tested as an antioxidant.…”

Section: Antioxidant Activitymentioning

confidence: 99%

A review on versatile applications of novel Schiff bases and their metal complexes

2019

Lett Appl NanoBioSci

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Metal complexes synthesized from Schiff bases and furthermore Schiff bases are versatile in nature. Such types of compounds were prepared from the condensation of an amino compound with carbonyl compounds (aldehyde or ketone) during which the carbonyl group is replaced by an imine or azomethine group. Schiff bases and their derivatives are widely employed in industries, polymers, dyes and medicative and pharmaceutical fields and additionally exhibit biological activities like antibacterial, antifungal, anti-inflammatory, antimalarial, antiviral, and antipyretic properties. Many Schiff base metal complexes exhibit glorious catalytic activities in numerous mechanisms. Their several applications in homogenous and heterogeneous catalysis were according troughout last decade. Several Schiff base complexes were helpful for their application as catalysts in reactions involving at high temperatures because of the high thermal and moisture stabilities. This text totally based on literature review with examples of the most promising applied Schiff bases and their complexes in several areas, summarizing the applications of Schiff bases and their numerous derivatives and complexes.

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“…The peak at 267 nm is attributed to π→π* transition and the peak at 325 nm is assigned to n →π* transition due to lone pair of electrons of an azomethine nitrogen and an antibonding p orbital. The complex showed an intense band at 394 nm due to the n-π* transition of azomethine chromophore and the band at 330 nm may be assigned as charge transfer band [29,30] . It has been reported that the metal is capable of forming dп-pп* bonds with ligands containing nitrogen as the donor atom.…”

Section: (F) Ir Spectra Of [Bic20h14o2n2] Complexmentioning

confidence: 99%

Synthesis, Spectral and Thermal Characterization on Bioactive Complexes of Mg(II), Zn(II), Sn(II), VO(II) and Bi(III) Ions Containing Schiff Base Ligand

2019

JCBSC

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Metal complexes of Mg(II), Zn(II), Sn(II), VO(II) and Bi(III) ions containing Schiff base ligand {2,2`((1E,1`E)-(1,2-phenylenebis(azanylylidene)) (methanylidene)) diphenol} were synthesized. The ligand was derived from the condensation reaction of salicylaldehyde and o-phenylenediamine. The ligands and metal complexes were isolated in solid state from the reaction medium. The Structural and spectral properties of ligand and complexes were confirmed by UV-Visible, FT-IR and some physiochemical measurements. IR spectral studies show the N and O atom of the Schiff bases are binding sites of ligand with the metal ion. Molar conductance measurements give evidence in favor of non-electrolytic nature of the complexes. The overall reactions were monitored by TLC analysis. Magnetic susceptibility data coupled with electronic spectra revealed that [ZnC20H14O2N2], [SnC20H14O2N2], [MgC20H14O2N2], [BiC20H14O2N2] complexes have tetrahedral geometry and [VOC20H14O2N2] complex has square planar geometry as well. Thermal analysis (TGA) data showed the possible degradation pathway of the complexes and also indicated that most of the complexes were thermally stable. The Schiff base ligands and their complexes were subjected to antimicrobial studies screened by using the disc diffusion method. Synthesis … Kismat Ara Elachi et al.

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Synthesis and evaluation of antioxidant and antimicrobial activities of Schiff base tin (II) complexes

Cited by 11 publications

References 11 publications

Ursolic Acid Hydrazide Based Organometallic Complexes: Synthesis, Characterization, Antibacterial, Antioxidant, and Docking Studies

Ursolic Acid Hydrazide Based Organometallic Complexes: Synthesis, Characterization, Antibacterial, Antioxidant, and Docking Studies

A review on versatile applications of novel Schiff bases and their metal complexes

Synthesis, Spectral and Thermal Characterization on Bioactive Complexes of Mg(II), Zn(II), Sn(II), VO(II) and Bi(III) Ions Containing Schiff Base Ligand

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