Synthesis and Characterization of Some New Heterocyclic Derivatives and Studying of their Biological Activity (Anti-Bacteria)

Behjet, Shaimaa A.; Khudair, Zahraa F.

doi:10.25258/ijpqa.11.1.6

Cited by 3 publications

(2 citation statements)

References 8 publications

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“…45 Higher extract concentrations may have lower actions because of the inundation of reactive centers of hydroxyl radicals, whereas those at more dilute concentrations have high activities because of the ease and quickness of their reactions. [46][47][48][49][50]…”

Section: Discussionmentioning

confidence: 99%

Exploring the Antioxidant Potential of Cissus woodrowii (Stapf Ex Cooke) Santapau: A Study on Leaves and Stem

Patil,

Singh,

Wadkar

2023

IJDDT

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Cancer, diabetes mellitus, cardiovascular disease, neurodegenerative illness, inflammatory disease, and many other pathologies have a common denominator: oxidative stress. The situation arises from the overproduction or ineffective quenching of free oxygen and nitrogen species within the cell. Antioxidant activity, nutritional value and traditionally roots were made into a powder and applied to cut wounds where pus had formed, ethnobotanical/traditional use is as an antitumor in Maharashtra. Owing to its ethnomedicinal importance, proper identification with pharmacognostic and phytochemical details and evaluation is vital for drug development and to prevent adulteration highlights and their role in laying down standardization. The present paper discusses phytochemical and antioxidant study of Cissus woodrowii (Stapf ex Cooke) Santapau. The both extract showed occurrence of glycosides, phenolic compounds, alkaloids, flavonoids also tannin and aqueous and ethanol extract of stem and leaves showed good antioxidant properties by DPPH assay.

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Section: Discussionmentioning

confidence: 99%

Exploring the Antioxidant Potential of Cissus woodrowii (Stapf Ex Cooke) Santapau: A Study on Leaves and Stem

Patil,

Singh,

Wadkar

2023

IJDDT

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“…FT-IR,spectrum,data for, derivative ,(B2) show,band,at 3300 cm -1, for (O -H ) 3080for (Ar -H) , 2985cm -1 for(C-H) inCH 3 ,1600 cm -1 or (C=N), 1593 cm -1 ,for . (C=C),1470cm -1 forN=N, 1 HMNR spectrum data of derivative (B2) show 2.52ppm (DMSO) , 1.9 (S ,3H, (OCH 3 ) 22…”

Section: Compound(b2) 2-(((z)-1-(24-dimethoxy-5-((e)-(4-methoxy-2-nitrophenyl)diazenylphenyl) Ethylidene)amino)phenolmentioning

confidence: 98%

Synthesis , Identification And Evaluation Of Antibacterial Activity For Some New Heterocyclic Derivatives From 4-Methoxy-2-Nitroaniline

Mezaal

Adnan²

2021

Al-Qadisiyah Journal of Pure Science

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This research involved synthesis. novel heterocyclic derivatives (quinazoline and thiazinone) derivatives , this compounds prepared from starting react (4-methoxy-2-nitroaniline) with 2,4-dimethoxyacetophenone to gate azo derivative (A) , (A) interact with aromatic amine derivatives to produce imine compounds (B1-B2), imine derivatives interact with (anthranilic acid , 2-mercaptobenzoic) to get heterocyclic derivatives quinazoline (C1-C2) and thiazinone (D1-D2 ) . All these compound characterized by13 C-NMR , FT-IR , 1HMNR . Then that,we studies the,biological,properties for,all heterocyclic derivatives,to,ward.two different kindof bacteria.

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Bazı Yeni Potansiyel Biyolojik Aktif 2-Etoksi-6-(3-substitue-4,5-dihidro-1H-1,2,4-triazol-5-on-4-il-azometin)-fenil Fenilasetat Türevlerinin Sentezi, Karakterizasyonu ve Antioksidan Özellikleri

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Kardaş

Manap

2022

EJOSAT

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1,2,4-Triazoller ve türevleri, tıbbi ve ilaç kimyası ve benzeri bir çok alanda ayrı bir yere sahiptir. Bunlar, çeşitli biyolojik aktivitelere sahip olan ve çok önemli roller oynayan çok sayıda heterosiklik bileşiğin sentezi için öncü bileşikler olarak da kullanılmaktadır. Bu çalışmada, trietilaminli ortamda yeni bir benzaldehid türevi olan 2-fenilasetoksi-3-etoksibenzaldehid bileşiğinin elde edilmesi için fenilasetil klorür ile 3-etoksi-2-hidroksibenzaldehitin reaksiyonu gerçekleştirilmiş olup sonrasında bu benzaldehid türevi ile literatürde mevcut olan dokuz tane amino bileşiğinin reaksiyonları sonucu heterohalkalı bileşiklerden 2-etoksi-6-(3-substitue-4,5-dihidro-1H-1,2,4-triazol-5-on-4-il-azometin)-fenil fenilasetat bileşiğinin sentezi gerçekleştirilmiştir. Çalışmanın devamında sentezlenen bazı 3 tipi bileşiklerin N-asetillendirme reaksiyonları da incelenmiş ve karşın olan 6 adet 2-etoksi-6-(1-asetil-3-substitue-4,5-dihidro-1H-1,2,4-triazol-5-on-4-il-azometin)-fenil fenilasetat bileşiklerinin sentezi gerçekleştirilmiştir. Bileşiklerin yapıları UV spektral verileri, 1H-NMR, 13C-NMR spektrumları ve IR verileri kullanılarak karakterize edildi. Bunun yanında 3c, 3f, 3i ve 4e bileşikleri için elementel analiz sonuçlarıda alınmıştır. Son olarak üç farklı yöntemle sentezlenen bileşiklerin in vitro potansiyel antioksidan aktiviteleri analiz edilmiştir.

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Synthesis and Characterization of Some New Heterocyclic Derivatives and Studying of their Biological Activity (Anti-Bacteria)

Cited by 3 publications

References 8 publications

Exploring the Antioxidant Potential of Cissus woodrowii (Stapf Ex Cooke) Santapau: A Study on Leaves and Stem

Exploring the Antioxidant Potential of Cissus woodrowii (Stapf Ex Cooke) Santapau: A Study on Leaves and Stem

Synthesis , Identification And Evaluation Of Antibacterial Activity For Some New Heterocyclic Derivatives From 4-Methoxy-2-Nitroaniline

Bazı Yeni Potansiyel Biyolojik Aktif 2-Etoksi-6-(3-substitue-4,5-dihidro-1H-1,2,4-triazol-5-on-4-il-azometin)-fenil Fenilasetat Türevlerinin Sentezi, Karakterizasyonu ve Antioksidan Özellikleri

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