Synthesis and characterization of soft polyurethane for pressure ulcer prevention

Pongmuksuwan, Pornlada; Harnnarongchai, Wanlop

doi:10.1016/j.polymertesting.2022.107634

Cited by 8 publications

(13 citation statements)

References 39 publications

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“…SEM–EDX analysis (Figure 3) showed that at 5 wt.% CLN, zeolite particles were randomly dispersed between the chains, while at 10 wt.% CLN concentration, they showed a tendency to agglomerate 65 . As a result, it can be interpreted that CLN particles contribute negatively to the orientation of the fibers during the uniaxial tensile test and it causes therefore a decrease in the strain at rupture value as they also reduce the ability to dissipate energy 66 . In the literature, the young modulus of cardiac and skeletal muscle was reported 100.3 ± 10.7 and 24.7 ± 3.5 kPa, 67 respectively.…”

Section: Resultsmentioning

confidence: 99%

“…It was determined that the swelling rate of the material decreased by doping the structure with CLN due to the CLN additive which acts as a cross‐link between the TPU chains, and leads to the formation of hydroxyl terminal chains 66,73 …”

Section: Resultsmentioning

confidence: 99%

“…65 As a result, it can be interpreted that CLN particles contribute negatively to the orientation of the fibers during the uniaxial tensile test and it causes therefore a decrease in the strain at rupture value as they also reduce the ability to dissipate energy. 66 In the literature, the young modulus of cardiac and skeletal muscle was reported 100.3 ± 10.7 and 24.7 ± 3.5 kPa, 67 respectively. The mechanical properties of the prepared materials in this study are therefore suitable for use in muscle tissue engineering.…”

Section: Mechanical Analysis Of Cln/tpu Nanofibrous Scaffoldsmentioning

confidence: 99%

“…The increase in the mass of TPU membrane doped with 10% CLN was 2.23 ± 0.33% at the end of the 1st hour, 3.09 ± 0.18% at 24 h, and 3.39 ± 0.21% at 48 h. It was determined that the swelling rate of the material decreased by doping the structure with CLN due to the CLN additive which acts as a cross-link between the TPU chains, and leads to the formation of hydroxyl terminal chains. 66,73…”

Section: The Water Retention Capacity Of Cln/tpu Nanofibrous Scaffoldsmentioning

confidence: 99%

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Fabrication of electrospun nanofibrous clinoptilolite doped thermoplastic polyurethane scaffolds for skeletal muscle tissue engineering

Yıldırım,

Sanli,

Türkoğlu

et al. 2023

J of Applied Polymer Sci

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The treatment of skeletal muscle, which lost its function with damage or trauma with autologous muscle tissue transfer, is a very problematic approach.Hence, it is critical to develop materials that are mimicking muscle tissue mechanical behaviors and allowing cell adhesion. Polyurethanes (PUs) are one of the most common polymers in tissue engineering applications and skeletal muscle regeneration due to their elasticity and mechanical flexibility. Clinoptilolite (CLN) is a hydrated alumina silica crystal based biocompatible material that numerous positive effects on animal and human health. Here, we report the synthesize of flexible membranes based on clinoptilolite (CLN) doped thermoplastıc polyurethane (TPU) nanofiber network to be used in the field of skeletal muscle regeneration. We primarily evaluated their ability to mimic skeletal muscle by determining their mechanical properties and cell adhesion rates. We observe that cell adhesion and proliferation increased with the increase of CLN contribution. Young modulus (E Y ) values of pure TPU, 5 and 10 wt.% CLN-doped TPU fibers are 3.66, 2.37, and 1.85 MPa, respectively. Mechanical elongations at break of pure TPU, 5 and 10 wt.% CLN-doped TPU fibers after 37 C treatment (7th day) are 193.41%, 113.30%, and 197.15%, respectively. With the addition of 5 wt.% CLN, the thermal stability slightly increased compared to the pure TPU and 10 wt.% CLN/TPU. In addition, cytotoxicity studies reveal that CLN/PU membranes are biocompatible, and finally cell adhesion increases proportionally to the increased CLN contribution. The obtained results indicate that the CLN/PU membranes can be used as a skeletal muscle scaffold.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Mechanical Analysis Of Cln/tpu Nanofibrous Scaffoldsmentioning

confidence: 99%

Section: The Water Retention Capacity Of Cln/tpu Nanofibrous Scaffoldsmentioning

confidence: 99%

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Fabrication of electrospun nanofibrous clinoptilolite doped thermoplastic polyurethane scaffolds for skeletal muscle tissue engineering

Yıldırım,

Sanli,

Türkoğlu

et al. 2023

J of Applied Polymer Sci

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“…RPU1 having higher soft segment content, induced better flexibility for the polymer chain and facilitated the polymer chain to be stretched to the higher strain leading to better elongation. However, in the case of RPU3, incorporating more aromatic IBHE reduced the flexibility of the polymer chain, inducing higher stress for breaking the polymer films [28,29].…”

Section: Resultsmentioning

confidence: 99%

Synthesis and characterization of non-invasively traceable poly(ether urethane)s for biomedical applications

Ghuge

Naik

et al. 2023

Biomed. Phys. Eng. Express

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The ease of real-time visibility of biomedical implants and minimally invasive medical devices is indispensable in radiological imaging to avoid complications and assess therapeutic success. Herein, we prepared a series of polyurethane elastomers with inherent radiopacity, enabling them to be imaged under fluoroscopy. Through an appropriate selection of less toxic intermediates such as 1,6-Diisocyanatohexane (HDI), poly (tetramethylene glycol) (PTMG), and a chain extender, iodinated hydroquinone bis(2-hydroxyethyl) ether (IBHE), new radiopaque polyether urethanes (RPUs) containing about 10.8 to 20.6 % iodine contents were synthesized. RPUs were characterized for the physicochemical, thermomechanical and radiopacifying properties. It was observed that the concentration of IBHE had a profound impact on the radiopacity of polyurethanes. RPUs exhibited similar or better radiopacity than an aluminum wedge of equivalent thickness. In-vivo imaging revealed that the RPUs were easily distinguishable from the surrounding tissues. Irrespective of iodine content, all the RPUs were cytocompatible, indicating the suitability of these materials for medical and allied applications.

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Particleboards based on agricultural and agroforestry wastes glued with vegetal polyurethane adhesive: An efficient and eco-friendly alternative

Faria,

Gonçalves,

Maffioletti

et al. 2024

Industrial Crops and Products

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Synthesis and characterization of soft polyurethane for pressure ulcer prevention

Cited by 8 publications

References 39 publications

Fabrication of electrospun nanofibrous clinoptilolite doped thermoplastic polyurethane scaffolds for skeletal muscle tissue engineering

Fabrication of electrospun nanofibrous clinoptilolite doped thermoplastic polyurethane scaffolds for skeletal muscle tissue engineering

Synthesis and characterization of non-invasively traceable poly(ether urethane)s for biomedical applications

Particleboards based on agricultural and agroforestry wastes glued with vegetal polyurethane adhesive: An efficient and eco-friendly alternative

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