Synthesis and characterization of biologically active new Schiff bases containing 3‐functionalized 1,2,4‐triazoles and their zinc(II) complexes: crystal structure of 4‐bromo‐2‐[(E)‐(1H‐1,2,4‐triazol‐3‐ylimino)‐ methyl]phenol

Metal-based ethanolamine-derived compounds: a note on their synthesis, characterization and bioactivity

“…The Schiff bases are characterized by an imine group and are formed as a condensation product 2 of primary amine with an aldehyde or ketone in the presence of a dehydrating agent such as MgSO 4 . A number of Schiff's base metal complexes have displayed bioactivity as antibacterial 3,4 , antifungal 5 , anticancer 6,7,8 , anti-inflammatory 9 , anticonvulsant 10 , antiviral 11 and analgesic 12 agents. Although metal-based ethanolamines have historically been subjected of many investigations 13,14 due to their use as buffers 15 , catalysts 16 , inhibitors 17 , ion exchangers 18 , electroplating and dyes 19 , now they are garnering attention for their biological 20 role in plant growth 21 regulation, bacterial and fungal metabolism and as a cytotoxic agent 22 .…”

Design, synthesis andin vitrobactericidal/fungicidal screening of some vanadyl(IV)complexes with mono- and di-substituted ONS donor triazoles

“…218-219 C; IR (KBr, cm 4 .5H 2 O (0.163g, 0.001 moles) was added. The mixture was refluxed for 3 h during which a precipitated product was formed.…”

“…Metal complexes have been the best choice so far in designing these candidates with remarkable biological potentials [1][2][3] . Variety of triazole derivatives represent an interesting class of compounds showing diversified clinical and pharmacological applications such as anti-bacterial 4 , anti-fungal 5 , anti-tumor 6 , anti-cancer 7 , anti-inflammatory 8 , anti-convulsant 9 , anti-proliferative 10 and analgesic properties 11 . Advances in medicinal properties of vanadium metal complexes have led to designing and use of its bioactive potential in metal-based drugs 12 .…”

Ligational behavior of new mononucleating NOO ethyl pyruvate Schiff base towards 3d metal(II) ions: an emphasis on antiproliferative and photocleavage property

“…This introduces a wider range of properties for these substances. The study of ligands involving such hydrazones is interesting as they demonstrate versatility in coordination and tendency to yield bioactive compounds . Numerous biological experiments have demonstrated that DNA is the primary intracellular target of anticancer drugs due to the interaction between small molecules and DNA, which cause DNA damage in cancer cells, blocking the division of cancer cells and resulting in cell death .…”