Synthesis and Characterization of a Novel Aminoketooxime Ligand and Enzymatic Efficiencies of Its Metal Complexes

Abstract

A novel aminoketooxime ligand and its mononuclear Cu(II) and Mn(II) complexes were synthesized. The structures of the synthesized compounds were illuminated by elemental analysis, inductively coupled plasma optical emission spectrometry, the Fourier transform infrared, 1 H-and 13 C-NMR, UV-Vis, magnetic susceptibility and conductivity measurements. According to the characterization studies ligand to metal ratio was found to be 2:1 with strong binding affinity of the ligand to the metal ions. In addition, complexes have been tested for their catecholase and phenoxazinone synthase-like activities. Kinetic studies were also carried out yielding Vmax, kcat and KM values of both complexes for catecholase and phenoxazinone synthase-like activities. Both complexes efficiently catalyzed the reactions of the enzymes they mimicked.

Synthesis, Spectroscopic Characterization And Antimicrobial Evaluation of Novel Nitrogen Containing Metal Complexes

“…The electronic spectrum of the Mn(II) complex (1) exhibits only one d-d transition band at 545 nm suggesting an octahedral geometry around Mn(II) ion [27,28], the octahedral geometry was proposed to the complex referring to its elemental, spectroscopic, analytical data and its empirical formula. The room temperature magnetic moment of complex (1) is 6.01 BM., is well within the range usually observed for octahedral Mn(II) (5.34-6.02 BM.)…”

“…The room temperature magnetic moment of complex (1) is 6.01 BM., is well within the range usually observed for octahedral Mn(II) (5.34-6.02 BM.) [27,28].…”