“…8 These synthetic building blocks address the challenge of bio-active structural complex molecule syn-thesis, 9 including indole diterpenoids shearinines 10 and paspalicines, 11 alstofolinine, 12 uprolide, 13 norhalichondrin, 14 ipomoeassin, 15 and glycosides. 2 Furthermore, pyranones are a vital intermediate in synthesizing medicines, such as aspergillides 16 and damone pheromones. 17 The Achmatowicz rearrangement (AR) reaction is the major method widely used to prepare pyranones from furfural alcohols (FALs), developed in 1971.…”