Synthesis and Biological Evaluation of New Pyrimidine Derivatives.

Abstract

Pyrimidine derivatives R 0510 Synthesis and Biological Evaluation of New Pyrimidine Derivatives. -Some of the new pyrimidine derivatives (III), (V) and (VIII) show cytotoxic and/or antimicrobial activity. -(FATHALLA*, O. A.; RADWAN, H. H.; AWAD, S. M.; MOHAMED, M. S.; Indian J. Chem., Sect. B: Org. Chem. Incl. Med. Chem. 45 (2006) 4, 980-985; Dep. Med. Chem., Natl. Res. Cent., Dokki, Cairo, Egypt; Eng.) -M. Kowall 33-166

Synthesis, Characterisation and Antimicrobial Evaluation of 4-(Substituted Phenyl)-N-(Substituted Phenyl)-6-Methyl-2-Oxo-1,2,3,4-Tetrahydropyrimidine-5-Carbohydrazide Derivatives

“…Pyrimidines and their derivatives are considered to be important for drugs and agricultural chemicals. Pyrimidine derivatives possess several interesting biological activities such as antimicrobial, antitumour and antifungal activities [1][2][3][4][5][6][7] . Many pyrimidine derivatives are used for thyroid drugs and leukemia.…”