Synthesis and Applications of Chalcogenoamide: Thio-, Seleno- and Telluroamides

Abstract

This provides a comprehensive survey of the recent progress in the various synthetic methods of the chalcogenoamides (thioamide, selenoamide and telluroamide), their application in the preparation of heterocycles and their biological significances.

Synthesis of Heterocyclic Thioamides and Copper(II) Coordination Compounds Based on Them

“…It is the reason for searching new methods of thioamides synthesis, their effective using in the coordination chemistry of 3d-metals [5] and obtaining compounds with a set of new chemical and physical properties. Previously the heterocyclic thioamides were obtained via thermal [6] or catalytic [3,4] activation of elemental sulfur according to Eq. (1):…”

Decoding Directing Groups and Their Pivotal Role in C−H Activation

“…[270] Thioamides have their importance as building blocks for the synthesis of heterocyclic compounds. [271,272] and are motifs present in biologically active compounds. [273,274] These com-Scheme 45.…”

Synthesis of orthogonally protected thioamide dipeptides for use in solid-phase peptide synthesis

“…6 The synthesis of thioamides has been reviewed, and one of the principal methods used is the thionation of amides. 7 A large number of methods have been developed for the thionation of carbonyl groups to their thiocarbonyl analogues, where the main reagents include Lawesson's reagent, 8 Berzelius' reagent 9 , more recently Curphey's method. 10 The use of a P4S10-pyridine complex was also reported by Bergman and co-workers in 2011.…”