Synthesis and application of new reactive disperse dyes based on isatin derivatives and their Antibacterial activity

Abstract

A NEW two reactive disperse dyes based on a hybrid structure of isatin and benzanthrone or anthraquinone via 1, 3, 5 triazine spacer were prepared. The prepared compounds were characterized by 1 H-NMR, mass spectrometry and elemental analysis. The UV/vis absorption spectra and emission spectra were measured in N, N-dimethylformamide (DMF) solution at room temperature, the effects of substituent's on the emission spectra of these compounds were interpreted. The dyeing application of the prepared dyes on wool and polyamide-6 fabrics at various concentrations of dye and different pH were investigated as well as the exhaustion and dye fixation were studied. The antibacterial activity of the prepared reactive disperse dyes were studied against different kind of bacteria such as Staphylococcus aureus (Gram-positive bacteria) and Escherichia coli (Gram-negative bacteria). The antibacterial affinity of the prepared dyes was exhibit a significant effect compared with selected antibiotics as reference standard. The fastness properties of the dyed fabrics were studied which showing excellent wash fastness, rubbing and perspiration fastness as well as high stability to light.

Synthesis And Characterization Of New 1,2,4- Triazine Based On 2,5-Dihydrazino-1,3,4- Thiadiazole

“…It was found that the hetero dienophile must be prepared firstly although the reaction between 2,5-dihydrazino -1,3,4-thiadiazole and substituted benzaldehyde in acidic media in ratio (1:2) under reflux condition for (2 hrs) , whereas the hetero diene prepared at room temperature with stirring between hydrazine hydrate and substituted benzaldehyde in ratio (1:2) these two starting materials hetero diene and dienophile were undergoes Diels-Alder reaction via grinding and MWI technique as summarized in the following Scheme: Firstly, Schiff bases prepared through condensation reaction in acidic media. The structure of Schiff bases (3)(4)(5)(6) were established on the bases of their spectroscopic data, they show in FT-IR spectroscopy stretching vibration bands at (1653-1618 cm -1 ) due to the C=N functional group and stretching vibration band at (3316-3050 cm -1 ) due to the only NH functional group . Actually these Schiff bases were underwent Diels-Alder reaction with hetero dienes (7,8) under grinding for (30min) and then free-Solvent MWI with power (720 watt) at specific time to offered the hetero adducts (9-20) through one step intercyclization reaction , as shown in Scheme (1).…”

“…Synthesis of (9-20): (Lenardao, Lara et al 2007)Equimolare of compounds (3)(4)(5)(6) and dibenzylidine hydrazine(7&8) were grinding for (30min) followed by irradiation in a microwave oven for suitable time at (720 watt). Cooling then cold water was added to the reaction mixture, and the solid product was then filtered off and recrystallized from ethanol.…”

Schiff Base Conjugate of 5-Fluoroisatin with Thiophene-2-Ethylamine and its Mannich Bases: Synthesis, Molecular Docking, and Evaluation of in vitro Anti-inflammatory and Anti-tubercular Activity

“…[1][2][3][4] Anti-tubercular and anti-inflammatory activities of heterocyclic hybrids with isatin (indole-2,3-dione) are being studied extensively. 5,6 The Mannich bases of isatin shows potent anti-tubercular activities in previous studies. 7,8 Anti-tubercular and anti-inflammatory properties of isatin and thiophene derivatives have been reported in the literature.…”

Optimization of Enzymatic Treatment and Reactive Dyeing of viscose fabric in One-bath Process

“…However, the large water consumption makes this process particularly not attractive on ecological grounds. In order to achieve effective production process, the fabric requires separately pretreatment bath to fabric has satisfactory levels of wetability, swelling and reduction of fibrillation tendency, which in turn, lead to a better dye uptake and increase the forces of dye-fiber interactions [11][12][13][14][15][16]. Moreover, several attempts have been made to sho exhaust two-bath processes of pretreatment and dyeing viscose into one-bath process.…”