Synthesis and Antimicrobial Activity of 10-N-Arylaminomethyl - 1,3,7,9 - Tetrachloro / H-Phenothiazines

Synthesis, Antibacterial and Antifungal Activity of 2-{1’-Aryl-1’-[4’’-(2’’’, 3’’’-Dichlorophenyl) Piperazin-Yl]-Methyl}-Cyclohexanone Hydrochloride

“…Taking into consideration diverse biodynamic activities such as analagesic 1 , antibacterial 2 , antidiabetic 3 , antifungal 4 , antialcer 5,6 , antihistaminic 7 , anthlminitic 8 , antiinflammatory 9 , antimicrobial 10 etc.The Mannich bases (4a-4l) have been synthesized by the condensation of 4-(2,3 ' -dichlorophenyl) piperazine hydrochloride, cyclohexanone with aromatic aldehyde in the presence of hydrochloric acid. All the products (4a-4l)were assigned with IR, 1 HNMR, Mass Spectra, TLC and Elemental analysis.…”