“…Anhydrous dichloromethane was purified using an MBRAUN Solvent Purification System MB SPS-800; acetone was dried over molecular sieves (3 Å); pyridine was dried over CaH 2 and distilled under nitrogen atmosphere. Indomethacin and ibuprofen acyl chloride, [49] (2-hydroxy-1,3-diaminopropane-κ 2 N , N ’)-dichloro platinum(II) [PtCl 2 (HO-pda)], [50] (ethane-1,2-diamine)-dichloro platinum(II) [PtCl 2 (en)], [51] ( SP -4-2)-( trans - R , R -cyclohexane-1,2-diamine)-oxalato platinum(II) [Pt(ox)(DACH)], [52] ( SP -4-2)-( trans - R , R -cyclohexane-1,2-diamine)-dihydroxo(oxalato) platinum(IV) [Pt(OH) 2 (ox)(DACH)], [53] and conjugates 3 and 4 [9] were prepared according to the respective published procedures. NMR spectra were recorded on a Bruker AVANCE DRX 400 (400 MHz), a Bruker AVANCE III HD (400 MHz) or a VARIAN Mercury 300 plus (300 MHz) spectrometer; 1 H and 13 C NMR spectra were referenced to tetramethylsilane (TMS) as internal standard; 195 Pt NMR spectra were referenced to Na 2 [PtCl 6 ] as external standard.…”