Synthesis and antibacterial activity of surface‐coated catechol‐conjugated polymer with silver nanoparticles on versatile substrate

Abstract

In the present study, 2-chloro-3′,4′-dihydroxyacetophenone (CCDP), a catechol derivative, was quaternized with poly(propylene oxide)-g-poly(dimethylaminoethyl methacrylate) (PPO-g-PDMA, PgP) to prepare surface coatings for various substrates. The surfaces of noble metals, oxides, and synthetic polymers were coated by immersion in an aqueous solution of CCDP quaternized with PgP (C-PgP). The catechol functional groups that remained on the surface were used for deposition of Ag nanoparticles (AgNPs) on the coated surface, to provide a water-resistant antibacterial polymer with long-term antimicrobial activity. X-ray photoelectron spectroscopy confirmed deposition of C-PgP and AgNPs on the surface coated with the antibacterial polymer. Surfaceimmobilized C-PgP/AgNPs showed outstanding antibacterial activities against Staphylococcus aureus, a Gram-positive bacterium, and Escherichia coli, a Gram-negative bacterium. C-PgP/AgNPs can be applied to a variety of substrates and can therefore be used as antibacterial materials in various fields.

Catechol-Functional Chitosan/Silver Nanoparticle Composite as a Highly Effective Antibacterial Agent with Species-Specific Mechanisms

“…The samples were dropped on the microscope slides (5 μL for each sample), covered with a cover slip, and imaged by a fluorescence microscope (LSM 510, Carl Zeiss). Images were obtained by a 10× objective lens 28 .…”

Synthesis and Properties of Cationic Gradient Brush Copolymers Carrying PEO Side Chains and Catechol Moieties

“…Exploring procedure presented in earlier publications, [ 42,43 ] ethanol and acetone were initially tested as possible solvents for the quaternization reaction. However, these solvents were not favorable for that reaction since the highest DQ was only 68%.…”

Antimicrobial Polymers in the Nano-World

“…The coating exhibited remarkable bacterial killing efficiency against S. aureus (ATCC 25923) and E. coli (ATCC 12435) after incubation for 24 h and showed stability up to 60 °C after 60 days in operation. Very recently, these authors [ 206 ] have successfully modified PP surfaces. The catechol derivative was quaternized with PPO- g -PDMAEMA and the remaining catechol groups were used to attach silver NPs.…”