Synthesis and Anti-Acetylcholinesterase Activity of N-[(indolyl)ethyl)-coumarin-yloxy)]Alkanamides

Abstract

Novel coumarin–tryptamine systems attached through a linker were synthesised and evaluated in vitro against acetylcholinesterase by the classical Ellman's test.

A One-Pot, Three-Component, Solvent-Free Synthesis of Novel 6H-Chromeno[3’,4’:5,6]Pyrido[2,3-d]Pyrimidine-Triones under Microwave Irradiation

“…Consequently, as a continuation of our ongoing efforts on the synthesis of heterocyclic compounds, [16][17][18][19][20][21][22] we report a one-pot and green protocol for the synthesis from reactants 1-3 of the novel heterocyclic system, chromeno [3',4':5,6]pyrido[2,3-d] pyrimidine 6,8,10(9H,11H)-triones 4a-h. This protocol uses the important tools in green chemistry of microwave irradiation and solvent-free conditions (Scheme 1).…”