Diaryl sulfides are a highly valuable class of sulfur‐containing compounds presented in numerous drugs with a broad range of therapeutic activities and are also employed as precursors to other higher oxidation state sulfur‐containing compounds with important bioactivities. Thus, the development of efficient approaches for C−S bond formation is essential in synthetic and medicinal chemistry. Many efforts have been made in constructing C−S bonds via various protocols. This review highlights the current strategies emphasizing metal‐catalyzed reactions (MRC), metal‐free approaches, photocatalysis reactions, and MCR's from 2012 onwards.
A series of novel benzofuran-1,2,3-triazole hybrids were synthesized and investigated as fungicidal preservatives. The compounds were evaluated for their antifungal potential against white-rot (Trametes versicolor), dry brown-rot (Poria placenta), and wet brown-rot (Coniophora puteana and Gloeophyllum trabeum) fungi, at different concentrations (500 ppm and 1000 ppm). The tests of the final products (8a, 8b, 8c, 8d, 8e, 8f, and 8g) demonstrated that compound N-((1-(4-fluorobenzyl)-1H-1,2,3-triazol-4-yl)methyl)benzofuran-2-carboxamide (8f) at a concentration of 500 ppm was the most active against wet brown-rot C. puteana (23.86% inhibition) and G. trabeum (47.16% inhibition) fungi. However, testing demonstrated that compounds 8a, 8b, 8c, 8d, and 8g at a concentration of 500 ppm did not exhibit acceptable antifungal effects against white-rot T. versicolor and dry brown-rot P. placenta fungi.
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''Chan-Evans-Lam'' (CEL) reaction is the copper-mediated cross-coupling of N-nucleophiles with boronic acids
that was independently reported in 1998 by Chan, Evans, and Lam for the first time. This reaction is accomplished at room
temperature with a remarkably wide range of nucleophiles. In the recent decade, it has been particularly attractive as a
convenient method for constructing the various C–N bonds in organic synthesis. Therefore, a comprehensive survey through
all reported process was crucial. In this review, we summarized research progress about N-Arylation, based on the type of
N-nucleophile involved in this reaction and catalysts from 2012 onwards.
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