Syntheses, X-ray crystal structures, DNA binding, oxidative cleavage activities and antimicrobial studies of two Cu(II) hydrazone complexes

Synthesis, spectral and thermal studies of some polymeric mixed ligand uracil–hydrazide complexes with transition metal ions

“…A shift to lower frequency (15-20 cm À1 ) in the position of ν(C=O) in the Bh-uracil complexes (Table 4) compared to the free ligand is indicative of the coordinated >C=O group [45]. However, the absence of ν(C=O) and appearance of a strong band between 1608-1618 cm À1 assigned as ν(C=N) in all the Inh-uracil complexes indicate that >C=O group is enolized and deprotonated [46]. The presence of a new band in the region 1286-1303 cm À1 due to ν(C-O À ) in the Inh-uracil complexes also suggest bonding to metal through the deprotonated C-O À group [47].…”

Synthesis, characterization, antioxidant, antimicrobial, DNA binding and cleavage studies of mononuclear Cu(II) and Co(II) complexes of 3-hydroxy-N'-(2-hydroxybenzylidene)-2-naphthohydrazide

“…The concentration of CT-DNA was determined from its absorption intensity at 260 nm with a known molar absorption coefficient value of 6600 dm 3 /mol.cm [24]. Stock solutions were stored at 4 °C and used over not more than 4 days.…”

“…arises from their significant antimicrobial, antiviral, antitubercular and anticancer activities [1][2][3][4]. Hydrazones and molecules having hydrazide residues in their structures are capable of showing antifungal, antibacterial activities and in the treatment of tuberculosis infections [5,6]. It is well narrated that azomethine associated with active hydrazone moiety showed anticancer bioactivity [7].…”

Transition Metal Complexes of (E)-N’-(4-cyanobenzylidene)nicotinohydrazide): Synthesis, Structural and Anti-Mycobacterial Activity Study

“…Hydrazones and their derivatives are considered as versatile class of compounds in organic chemistry with interesting biological properties, such as anti-inflammatory (Thomas et al, 2011), analgesic, anticonvulsant, antituberculous (Da Costa et al, 2012Gemma et al, 2009), antitumor (Torje et al, 2012), anti-HIV (Rollas and Kucukguzel, 2007) and antimicrobial activities (Banerjee et al, 2009;Mangalam et al, 2009). It has been recognized that metal complexes of the hydrazones may serve as models for biological important species (Rakesh et al, 2009).…”