Syntheses and Crystal Structures of 1,5-Dioxaspiro[5.5]undecane-2,4-dione Derivatives

Synthesis and Crystal Structures of Two Novel O, N-Containing Spiro Compounds

“…The double bond length C10-C8 (1.371(7) Å) in (1), (C7-C9) (1.366(2) Å) (2), is likewise in agreement with those described earlier reported (1.3454(2) Å, 1.336(2) Å) [15]. The double bond C10-N1 in (1) (1.308(7) Å), C7-N2 (2) (1.3248(18) Å) is typical C-N single bond.…”

“…The selected bond distances and bond angles of 1 and 2 are listed in Table 1 described earlier reported (1.3454(2) Å, 1.336(2) Å) [15]. The double bond C10-N1 in (1) (1.308(7) Å), C7-N2 (2) (1.3248(18) Å) is typical C-N single bond.…”

“…The intermediate compound (1,5-dioxaspiro[5.5]undecane-2,4-dione) was prepared according to our earlier report [16]. The synthesis of two title compounds are described below.…”

“…Application of spiro compounds in industry [11,12], catalysis [13] and hole-transporting materials [14] has been triggered great interest in recent years. For these reasons, our group has developed a new simple strategy to synthesize various spiro compounds [15][16][17]. However, to the best of our knowledge, among so many reported spiro-compounds, O, N-Containing spiro compounds derived from 1,5-dioxaspiro [5.5]undecane-2,4-dione are very rare.…”

Synthesis and Crystal Structures of Two New Oxaspirocyclic Compounds

“…The presence of oxaspirocyclic compounds in various natural products has also emerged, increasing interest due to their important biological activities, such as antimicrobial [9,10], antitumor [11] ,antiproliferative [12], antiviral [13], antiplasmodial [14] and antihistamic [15] activity etc. Based on these reasons, our group began to synthesize various oxaspirocyclic compounds and study their chemical properties [16][17][18][19]. In addition, to the best of our knowledge, oxaspirocyclic compounds derived from 6,10-dioxaspiro [4.5]decane-7,9-dione are very rare.…”