Synthesis and Crystal Structures of Two New Oxaspirocyclic Compounds

Abstract

Abstract:Two new oxaspirocyclic compounds, 8-(4-(dimethylamino)benzylidene)-6,10-dioxaspiro [4.5] decane-7,9-dione (1) and 8-(4-hydroxybenzylidene)-6,10-dioxaspiro[4.5]decane-7,9-dione (2) have been synthesized and their structures determined by single crystal X-ray crystallography. Compound 1, C 17 H 19 NO 4 , belongs to the monoclinic system, space group P21/c with a = 6.2554 (13)

Synthesis and Crystal Structure of a New Hydrated Benzimidazolium Salt Containing Spiro Structure

“…The strong bands at 1675 cm −1 and 1218 cm −1 are attributed to the stretching vibrations of C=O and C-O bands of 1,3-dioxane ring, which conforms to our earlier report [16,17]. The title compound exhibits strong bands at 1493 cm −1 (C=C), 1441 cm −1 (C=N), 779 cm −1 (υ C-H benzene ring) and 744 cm −1 (υ C-H imidazole ring) for the benzimidazolum group [18].…”

“…The title compound is not planar. (17) torsion angles are −167.65(2)°, −170.89(2)°, −16.7(3)° and −11.9(2)°, respectively. The two cyclohexane rings both exhibit a chair-like configuration, with puckering parameters for ring 1 (C8−C13): Q = 0.565 (6) Å, q2 = 0.025 Å, q3 = −0.565 Å, ϑ = 177.5°, ϕ = 69.43°; ring 2 (C21−C26): Q = 0.556 Å, q2 = 0.037 Å, q3 = −0.555 Å, ϑ = 176.2°, ϕ = 168.05° [15].…”

Design and Crystal Structures of Two New Compounds Fused with 3,4,5-Trimethoxybenzyl Group and 6,10-Dioxaspiro Group

“…J1 is easily obtained by a literature known method [14]. A 100 mL round-bottomed flask was charged with 3,4 5-trimethoxybenzaldehyde (0.98 g, 5 mL), 6,10-dioxaspiro [4,5]decane-7,9-dione(0.85 g, 5 mL), and ethanol (15 mL).…”

“…Packing arrangement in the unit cell of J1 and J2 are displayed in Figure 2, respectively. 128.22 (15) 109.48(13) C(10)-C(12)-C (11) 114.83 (14) 113.71(15) C(13)-C(12)-C (11) 116.91 (14) 112.53(13) As can be seen from Figure 1, two compounds both comprise the 3,4,5-trimethoxybenzyl group and the dioxaspiro group. From the bond length data, the C10-C12 bond length of 1.535(2) Å (J2) is longer that of 1.359(4) (J1), which indicates that the 3,4,5-trimethoxybenzyl group connects with the dioxaspiro group by the central C(10) atoms via double bond (J1) and single bond (J2), respectively.…”

“…For these reasons, for 10 years, our group has exploited several approaches to synthesize all kinds of spiro compounds [13][14][15][16]. In continuation of our work, two new compounds: 8-(3,4,5-trimethoxybenzylidene)-6,10-dioxaspiro [4,5]decane-7,9-dione (J1) and 8-(3,4,5trimethoxybenzyl)-6,10-dioxaspiro [4,5]decane-7,9-dione (J2) have been prepared via different synthetic routes (Scheme 1).…”