Synthesen in der Carotinoid‐Reihe. 13. Mitteilung Synthese von Canthaxanthin

Zeller, P.; Bader, F. E.; Lindlar, H.; Montavon, M.; Müller, P. B.; Rüegg, R.; Ryser, G.; Saucy, G.; Schaeren, S. F.; Schwieter, Ulrich; Stricker, K.; Tamm, R.; Zürcher, P.; Isler, O.

doi:10.1002/hlca.19590420326

Cited by 32 publications

(4 citation statements)

References 9 publications

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“…Many crustacean species contain considerable quantities of carotenoid compounds such as astaxanthin and canthaxanthin (Thommen and Wackernagel 1964a, b, Goodwin 1984 which have light absorptive properties within the excitation range of FAP compounds (Cooper et al 1975, Zeller et al 1959 and are highly soluble in non-polar solvents such as chloroform. Thus, these carotenoid compounds could possibly cause internal quenching of FAP fluorescence.…”

Section: Discussionmentioning

confidence: 99%

Critical aspects of fluorescent age-pigment methodologies: Modification for accurate analysis and age assessments in aquatic organisms

Hill

Womersley

1991

Mar. Biol.

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Abstract. Fluorescent age-pigment (FAP) quantification has recently been proposed as a means of estimating age in aquatic vertebrates and invertebrates. However, various aspects related to currently adopted procedures remain untested and a distinct relationship between FAP accumulation and chronological age has yet to be established. The present study was undertaken to critically evaluate the effects of specimen and extract handling procedures (including temperature, time, ultrasonication, and solvent systems) on the expression of native FAP fluorescence using the post-mitotic tissues of laboratoryreared specimens of the teleost Oreochromis mossambicus as model systems. FAP-like fluorophores increased in vitro in brain, heart, and muscle tissues and their extracts with increased storage temperature (-20 °C and above) and time. Sonification of homogenates greatly enhanced this effect and generated other non-native fluorophores in sample solution. Fluorescence assay temperature also affected expression of results, and aqueous-phase extracts, used in previous studies, were found to contain large amounts of fluorescent flavin contaminants. Using modifications of the above procedures, age-related patterns of accumulation were subsequently examined in O. mossambicus brain and, for the first time, positive correlations between chronological age and whole organ as well as weight-specific FAP concentration were validated. The significance of these findings are discussed in relation to previous FAP studies.

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Section: Discussionmentioning

confidence: 99%

Critical aspects of fluorescent age-pigment methodologies: Modification for accurate analysis and age assessments in aquatic organisms

Hill

Womersley

1991

Mar. Biol.

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“…Five other carotenoids, two C 40 symmetrical carotenoids and three apocarotenoids (Figure ), are also produced commercially in the nutraceutical industry as food products (vitamin supplements, feed additives for poultry, livestocks, fish, and crustaceans) and as cosmetics: C 30 8′-apo-β-carotenal ( 13 ) (cheese, dressings), C 30 ethyl 8′-apo-β-carotenoate ( 642 ) (poultry-egg yolk and broiler skin pigmentation), , C 33 citranaxanthin ( 643 ) (poultry-egg yolk pigmentation), , C 40 canthaxanthin ( 561 ) (poultry), and a mixture of stereoisomers of C 40 astaxanthin ( 644 ) (aquaculture-salmonoidae, crustaceae) . The synthesis of enantiopure (3 S ,3′ S )-astaxanthin ( 528 ) has been developed at BASF.…”

Section: Synthesis Of Carotenoidsmentioning

confidence: 99%

Functions, Therapeutic Applications, and Synthesis of Retinoids and Carotenoids

et al. 2013

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“…[12] Methylmalondialdehyde tetraethyldiacetal [22,23] was used instead of free methylmalondialdehyde. Methylmalondialdehyde tetraethyldiacetal (3.5 equiv.)…”

Section: -Methyl-10-oxo-910-dihydropyrimido[12-a]purine (5)mentioning

confidence: 99%

Syntheses of 7‐(2‐Hydroxy‐1‐phenylethyl)‐ and 7‐(2‐Hydroxy‐2‐phenylethyl)guanine, DNA Adducts Derived from Styrene 7,8‐Oxide

2004

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Abstract7‐(2‐Hydroxy‐1‐phenylethyl)‐ and 7‐(2‐hydroxy‐2‐phenylethyl)guanines are important DNA adducts which can be used as markers of exposure to styrene. Two synthetic routes leading to these compounds are presented using allyl‐protected bromohydrins as synthetic equivalents of styrene oxide to alkylate 2‐amino‐6‐chloropurine or 7‐methyl‐10‐oxo‐9,10‐dihydropyrimido[1,2‐a]purine as precursors to guanine. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004)

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Synthesen in der Carotinoid‐Reihe. 13. Mitteilung Synthese von Canthaxanthin

Cited by 32 publications

References 9 publications

Critical aspects of fluorescent age-pigment methodologies: Modification for accurate analysis and age assessments in aquatic organisms

Critical aspects of fluorescent age-pigment methodologies: Modification for accurate analysis and age assessments in aquatic organisms

Functions, Therapeutic Applications, and Synthesis of Retinoids and Carotenoids

Syntheses of 7‐(2‐Hydroxy‐1‐phenylethyl)‐ and 7‐(2‐Hydroxy‐2‐phenylethyl)guanine, DNA Adducts Derived from Styrene 7,8‐Oxide

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