Synthèse des 2-F-alkyléthylamines: optimisation de l'obtention des azotures de 2-F-alkyléthyle et de leur réduction en amines

Fluorinated organic azides – their preparation and synthetic application

“…The synthesis and characterization of azide 16 prepared from iodide 11 is presented in this paper. On the other hand preparation of 1H,1H,2H,2H-perfluorooctyl azide 9 from the corresponding iodide 12 with sodium azide and Aliquat® 336, [55][56][57] in DMF, 14,58 in DMSO 45 or methyl-tridecylammonium chloride 59 has already been described. Prepared or purchased iodides were submitted to nucleophilic substitution with sodium azide.…”

Synthesis of 3,3,4,4-tetrafluoro-4-iodobutylamine, a bifunctional reagent for ionic and free-radical reactions

“…TEBA proved to be as efficient as the phase transfer catalysts used earlier. 5, 6 The selective replacement of the iodine atom in the group CH 2 I was confirmed by NMR and mass spectra. In the 1 H NMR spectrum of iodo azide 3, the chemical shift of the termi nal CH 2 group is appreciably different from that for di iodide 2, while the 19 F NMR spectrum remains virtually unchanged (for the NMR spectra of diiodide 2, see Ref.…”

Ethylene-tetrafluoroethylene (ETFE) cotelomer iodides and their transformation to surface protection intermediates

“…etc. could be extended to ETFE cotelomer iodides with minor modification [33][34][35][36][37][38]. However, there are major difficulties associated with, particularly with regard to the poor solubility of the ETFE cotelomer iodides in some of the organic solvents used as medium for these transformations.…”

“…The transformation of the iodide to the azide was initially attempted under phasetransfer conditions, as described in the literature for telomer iodides [36]. However, this reaction failed to give good yield of the azide and only 10% conversion was observed.…”