Synovial sarcoma of the heart

Abstract

Primary cardiac tumors are of rare presentation. We present a case of synovial sarcoma of the right atrium treated in our institution. An initial diagnosis of right atrial myxoma was made based on clinico-radiological features. Intra-operatively, an irregular mass was found. Histopathologically, it was reported as monophasic synovial sarcoma. Immunohistochemistry was positive for S-100, B-cell lymphoma-2, MIC-2 and calretinin. Patient received adjuvant chemotherapy and is currently free of disease for 2 years and on regular follow-up.

Primary cardiac atrial sarcomas. Report of two histologically different cases and review of the literature

“…The prognosis of SS is extremely unfavorable with majority of patients dying shortly after diagnosis and only few patients with an observation time close to a year [50]. That makes our case special among only few others as current observation since the initial surgery is more than two years [62]. The reason of such poor survival can also be assigned to low radical surgery frequency resulting from tumour location [50].…”

High-Grade Pleomorphic Sarcoma of the Left Atrium after Incomplete Resection and Adjuvant Chemotherapy

“…21 MRI and CT demonstrate the extent of the tumor in the myocardium and the presence of metastases. 22 The diagnosis of sarcoma is only made after histological analysis, but there are characteristics of radiological tests to differentiate it from the myxoma, such as the non-septal connection of the mass, multiple masses, extensive connection to the left atrial wall, extension to the pulmonary vein, and semi-solid consistency. 23 Moreover, gastrointestinal symptoms appear more in UPS than in myxomas.…”

High-Grade Left Atrial Pleomorphic Sarcoma: Case Report and Review

“…As an initial diagnostic approach, echocardiography could be a useful tool. Magnetic resonance imaging of heart could be utilized in the evaluation of cardiac masses, as it provides contrast resolution to soft tissues and can evaluate extension to the myocardium [14]. Transesophageal echocardiography has proven to be a noninvasive and relatively effective tool [15].…”