Synergistic reinforcement of polydopamine-coated hydroxyapatite and BMP2 biomimetic peptide on the bioactivity of PMMA-based cement

Kang, Ting; Hua, Xiaoli; Liang, Peiqing; Rao, M.S.; Wang, Qin; Quan, Changyun; Zhang, Chao; Jiang, Qing

doi:10.1016/j.compscitech.2016.01.002

Cited by 30 publications

(12 citation statements)

References 35 publications

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“…Although the EBC showed the lower compressive strength than PMMA, the deteriorated compressive strength (<70 MPa) of composite with PMMA bone cement also existed in other related literature. [23][24][25] The value was still in the range of the cancellous bone and the cortical bones (10.44-153.59 MPa), which still provided enough support to human bones. [26,27] In addition, the expansion stress during the swelling process of the expandable PMMA-based bone cement could be used as a prestress to resist the external force, which compensated the decreased compressive strength of composite bone cement to a certain extent.…”

Section: Mechanical Propertiesmentioning

confidence: 99%

Swelling behavior of expandable poly(methyl methacrylate‐acrylic acid)/polymethyl methacrylate bio‐composites with different crosslinking densities

Chen

Tang

Zhao

et al. 2020

J of Applied Polymer Sci

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The volume shrinkage of poly(methyl methacrylate‐acrylic acid) (PMMA) bone cement was mainly tackled by the different types and contents of the hydrophilic additives. While the crosslinking density was assumed to regulate the hydrophilic group amounts and 3D network structures in the additives, which influenced the absorption and swelling capacity of the PMMA‐based bone cement. In this study, the expandable PMMA/polymethyl methacrylate bio‐composites (EBC) with different N, N‐methylenebisacrylamide (MBA) contents were synthesized to investigate the relationship between the crosslinking density and swelling performance, and also promoted the absorption and swelling properties before the solidification of EBC. The results demonstrated that the equilibrium absorption ratio and the equilibrium swelling ratio both exhibited a normal distribution with the various MBA content. In addition, the controlled absorption ratio (7.3–60.2%) and swelling ratio (8.5–61.8%) of EBC could be obtained by altering crosslinking density in the system. Furthermore, EBC could obtain a similar equilibrium absorption ratio and equilibrium swelling ratio with different mechanical properties, which provided more options for meeting the requirements of EBC in different clinical settings.

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Section: Mechanical Propertiesmentioning

confidence: 99%

Swelling behavior of expandable poly(methyl methacrylate‐acrylic acid)/polymethyl methacrylate bio‐composites with different crosslinking densities

Chen

Tang

Zhao

et al. 2020

J of Applied Polymer Sci

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“…Kang et al 141 . examined the influence of polydopamine (pDA)‐coated HA and BMP‐2 mimicking peptides on the apatite formation ability of PMMA‐based BCs.…”

Section: Composite‐based Bcsmentioning

confidence: 99%

Poly(methyl methacrylate) bone cement, its rise, growth, downfall and future

Bakhtiari

Bakhsheshi-Rad

Karbasi

et al. 2020

Polymer International

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Poly(methyl methacrylate) (PMMA)‐based bone cements (BCs) can be defined as a family of materials that consist of powder and liquid phases which after mixing form a plastic paste that can self‐set once implanted in the human body. PMMA‐based BCs are easily molded and adapted to complex bone cavities or used in orthodontic applications to restore dental damage. The main advantages of the use of cement are the excellent primary fixation between bone and implant and, therefore, the faster recovery of the patient. Despite the initial success rate of implant fixation with BCs, they have some disadvantages such as local tissue damage due to exothermic polymerization reactions, mechanical mismatch between native bone and cement, lack of bone regeneration and bioactivity and poor mechanical properties which may cause the failure of the BCs. BCs are still considered as a top option for bone repair. Due to the disadvantages highlighted, research has focused on alternative materials used with PMMA‐based BCs. This review aims to critically review the BCs and emerging materials used in combination with PMMA‐based BCs. These materials include titania, apatite–wollastonite (A‐W), glass ceramic (GC) and hydroxyapatite (HA). The review discusses the properties of these materials and their pathway to clinical study. Among the various kinds of reinforcement, HA has been extensively used. So, in this review, we compare the effects of HA as reinforcement in PMMA‐based BCs. Upcoming study of PMMA‐based BCs should concentrate on trialing combinations of these reinforcing agents as this might improve beneficial characteristics. © 2020 Society of Industrial Chemistry

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“…In Figure 4 (b), the surface morphological image of the nanocomposite 3 sample shows that the surface is transformed into a rough and porous structure (Radha et al, 2017). Increased surface pores in composite structures indicate improved mechanical properties and strong adsorption (Kang et al, 2016;Kim et al, 2004).…”

Section: Sem Analysismentioning

confidence: 99%

In Vitro Cytotoxicity Analysis and Synthesis of Biocidal Allicin/Mt/Mma/Peg/Poss Nanocomposites for the Food Packaging

Baysal

2020

Gıda

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In this study, the new nanocomposites were synthesized using antibacterial and antioxidant curcumin (Cr) and allicin (Ac), the high mechanical strength montmorillonite clay (Mt) and biocompatible methylmethacrylate (MMA), polyethylene glycol (PEG) and polyocta-hedral oligomeric silsesquioxanes (POSS) polymers. Firstly, monomer 1 was synthesized by using Ag + -montmorillonite, the curcumin extract and POSS, then the synthesized monomer 1 was interacted with MMA and PEG polymers, and nanocomposites were synthesized. The synthesized nanocomposites were analyzed by using the methods of Fourier Transform Infrared Spectroscopy (FTIR), X-ray diffraction (XRD) and scanning electron microscopy (SEM). After this, the inhibition zones and the surface activity resistances of the nanocomposites were analyzed against the bacteria Escherichia coli (E. coli), Listeria monocytogenes (L. monocytogenes), Salmonella and Staphylococcus aureus (S.aureus) and carried out biocompatibility analysis. According to the analysis results, the nanocomposites have been found to have the strong antibacterial resistance and biocompatibility.

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Synergistic reinforcement of polydopamine-coated hydroxyapatite and BMP2 biomimetic peptide on the bioactivity of PMMA-based cement

Cited by 30 publications

References 35 publications

Swelling behavior of expandable poly(methyl methacrylate‐acrylic acid)/polymethyl methacrylate bio‐composites with different crosslinking densities

Swelling behavior of expandable poly(methyl methacrylate‐acrylic acid)/polymethyl methacrylate bio‐composites with different crosslinking densities

Poly(methyl methacrylate) bone cement, its rise, growth, downfall and future

In Vitro Cytotoxicity Analysis and Synthesis of Biocidal Allicin/Mt/Mma/Peg/Poss Nanocomposites for the Food Packaging

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