Synchronous sporadic bilateral multiple chromophobe renal cell carcinoma accompanied by a clear cell carcinoma and a cyst: A case report

Yang, Fan; Zhao, Zichen; Hu, Ajin; Sun, Pengfei; Zhang, Bin; Yu, Mingchuan; Wang, Juan

doi:10.12998/wjcc.v8.i14.3064

Cited by 2 publications

(2 citation statements)

References 27 publications

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“…In the current case, we utilized a CT scan of the abdomen and pelvis using IV contrast to reveal the presence of several renal cysts of varying sizes within the right kidney. Like the present case, Yang et al described a synchronous bilateral chRCC with two histological variants, accompanied by a clear cell carcinoma and a cyst [20]. They utilized a contrast CT/MRI scan that showed a solid mass in the right kidney with well-defined margins and exophytic, circumscribed enhancing lesions.…”

Section: Discussionmentioning

confidence: 59%

Combined Clear Cell Renal Cell Carcinoma and Chromophobe Renal Cell Carcinoma: A Case Report

Meliti,

Alardati,

Khayat

et al. 2024

Cureus

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Renal cell carcinoma (RCC) is a diverse array of cancers arising from renal tubular epithelial cells. RCC presenting with distinct morphological subtypes, such as the simultaneous presence of chromophobe RCC (chRCC) and clear cell RCC (ccRCC) lesions within the same kidney, is rare. We present the case of a 79-yearold female with a history of breast cancer who presented to our facility with right flank pain. Further investigations using CT of the abdomen and pelvis revealed a Bosniak type 4 cyst with a mural nodule in the right kidney. Furthermore, another well-defined, solid lesion measuring 2.8 × 2.6 cm was observed in the same area. The patient underwent a right radical nephrectomy. The macroscopic examination of the kidney revealed the presence of three cysts, with the largest measuring up to 7.5 cm. Moreover, a distinctly demarcated, golden-yellow, solid mass was discerned in the superior pole of the kidney. The mass showed a heterogeneous cut surface with solid and cystic components, measuring 2.8 × 2.6 × 2.0 cm. A less extensive but well-defined, uniform tan mass was also identified within the wall of the largest cyst, which measured 1.2 × 1.0 × 0.7 cm. At this point, the diagnosis of ccRCC and chRCC was established.

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Section: Discussionmentioning

confidence: 59%

Combined Clear Cell Renal Cell Carcinoma and Chromophobe Renal Cell Carcinoma: A Case Report

Meliti,

Alardati,

Khayat

et al. 2024

Cureus

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show abstract

“…Если у пациентов изначально фиксируется опухоль большого размера или имеются признаки саркоматоидной трансформации, прогноз заболевания значительно ухудшается из-за возрастания риска метастазирования [42]. Зачастую хромофобные опухоли могут быть случайной находкой, поскольку чаще всего протекают доброкачественно и без выраженной клинической симптоматики [43]. По этой причине внимание исследователей сосредоточено не только на морфологических способах верификации диагноза, но и на различных молекулярных маркерах данного типа опухоли.…”

Section: хромофобный почечно-клеточный ракunclassified

Management of patients with multiple primary сancer in the practice of a modern oncologist. Case report and literature review

Хланта

Генс

2022

Sib. onkol. ž.

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The purpose of the study. Multiple primary malignant neoplasms or polyneoplasia are a phenomenon of tumorigenesis and one of the little-studied categories in modern clinical oncology. The increase in the cancer incidence, as well as the need to make difficult decisions about further treatment strategy, enhance the relevance of studying multiple primary malignant neoplasms. This review discusses the current positions of medicine in relation to this category of malignant neoplasms, and presents a case report of a patient with this disaese. Material and methods. We have analyzed the results of international studies on the management of patients with multiple primary cancer. the search for relevant sources was carried out in the Web of Science, Scopus, Medline systems with a chronological interval of 2016–2021. of the analyzed studies, 60 were used to compile a systematic review with a case report. Results. The analysis showed that timely diagnosis and improvement of cancer screening programs are necessary to improve the control of these tumors. Psychological work with a patient, strengthening of his commitment to therapy and the implementation of medical recommendations are integral parts of improving cancer care for patients with such disease. Conclusion. A comprehensive analysis of multiple primary malignant tumors requires long-term follow-up of a large population, taking into account genetic factors, environmental factors, exposure to smoking and nutrition, and comorbid pathology. Timely diagnosis and improvement of cancer screening programs are necessary to improve the control of multiple primary malignant tumors.

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Synchronous sporadic bilateral multiple chromophobe renal cell carcinoma accompanied by a clear cell carcinoma and a cyst: A case report

Cited by 2 publications

References 27 publications

Combined Clear Cell Renal Cell Carcinoma and Chromophobe Renal Cell Carcinoma: A Case Report

Combined Clear Cell Renal Cell Carcinoma and Chromophobe Renal Cell Carcinoma: A Case Report

Management of patients with multiple primary сancer in the practice of a modern oncologist. Case report and literature review

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