Synchronous primary adenocarcinoma of the appendix and colon: Case report and literature review

Abstract

Highlights Primary adenocarcinoma of appendix is rare pathology that is discovered usually on histopathologic examination of resected appendix. It is important to report all pathologic reports to the primary physician in order to confirm primary diagnosis and discuss it with their patients. If a diagnosis of PAA is reported, a surveillance lifelong colonoscopy screening is mandatory to rule out synchronous or metachronous occurrence of colonic malignances.

A case of appendix adenocarcinoma associated with ulcerative colitis

“…A preoperative diagnosis of appendix carcinoma has been reported to be extremely difficult, since there are no pathognomonic signs or symptoms. 21 In this case, a colonoscopy performed 1 year earlier revealed no evidence of appendix carcinoma. Since more than 70% of patients with appendix carcinoma present with clinical symptoms of acute appendicitis, 21 we should pay attention to such symptoms in the follow-up of UC patients presenting a skip lesion at the appendix orifice.…”

A case of appendix adenocarcinoma associated with ulcerative colitis.

“…A preoperative diagnosis of appendix carcinoma has been reported to be extremely difficult, since there are no pathognomonic signs or symptoms (1). In this case, a colonoscopy performed one year earlier revealed no evidence of appendix carcinoma.…”

Appendiceal Adenocarcinoma Presenting As Perforated Appendicitis

“…Patients can present with features of acute appendicitis, right lower quadrant mass, urinary frequency, or intussusception. In this case, the appendiceal mass acted in place of a fecalith to occlude the appendix and acted as the catalyst for an inflammatory process in the vestigial organ [ 7 ]. Appendiceal cancers that have spread, on the other hand, commonly present with vague abdominal pain and increased abdominal girth.…”