Synchronous invasive ductal carcinoma of the breast and clear cell renal carcinoma with rare presentation and behaviour: a case report with a literature review

Hassan, Mona Ali; Fakhrudiin, Najla; Farhat, Fadi

doi:10.3332/ecancer.2020.1120

Cited by 2 publications

(1 citation statement)

References 12 publications

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“…There are several case reports describing patients with both primary RCC and malignant breast neoplasms [4][5][6][7][8][9] . It is estimated that in the US 281,550 women and 2,650 men will be diagnosed with BC in 2021 10 .…”

Section: Introductionmentioning

confidence: 99%

Studying the association between breast cancer and renal cell carcinoma

Jazieh

Baidoun

Torrejon

et al. 2021

Breast Cancer Res Treat

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There are case reports of patients with both primary breast cancer (BC) and renal cell carcinoma (RCC).We explore the association between these two malignancies using SEER population data and our institutional records. Methods:We studied the association between BC and RCC in the 2000-2016 Surveillance, Epidemiology and End Results (SEER) database. We then reviewed our hospital records of patients with both BC and RCC and collected information including personal and family history of cancers, genetic testing, and patient outcomes. Results :Of the 813,477 females diagnosed with BC in the SEER database, 1,914 later developed RCC. The risk of developing RCC was signi cantly increased within the rst six months, 7-12 months, and 1-5 years following BC diagnosis with standardized incidence ratios (SIRs) of 5.08 (95% CI, 4.62-5.57), 2.09 (95% CI, 1.8-2.42), and 1.15 (95% CI, 1.06-1.24), respectively. Of 56,200 females with RCC, 1,087 later developed BC. The risk of developing BC following RCC was elevated within the rst six months (SIR of 1.45 [95% CI, 1.20-1.73]). For our hospital patients, 437 had both BC and RCC. 427 (97.71%) were female, and 358 (81.92%) were white, and breast cancer was diagnosed before RCC in 246 (61.5%) patients. There were 15 germline mutations in those with genetic testing. Conclusion:Our ndings suggest that BC patients are at higher risk of developing RCC and vice versa. BC tended to precede RCC, and patients frequently had personal histories of other malignancies and a family history of cancer, particularly BC.

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Section: Introductionmentioning

confidence: 99%

Studying the association between breast cancer and renal cell carcinoma

Jazieh

Baidoun

Torrejon

et al. 2021

Breast Cancer Res Treat

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Studying the Association Between Breast Cancer and Renal Cell Carcinoma

Jazieh

Baidoun

Torrejon

et al. 2021

Preprint

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Purpose: There are case reports of patients with both primary breast cancer (BC) and renal cell carcinoma (RCC). We explore the association between these two malignancies using SEER population data and our institutional records.Methods: We studied the association between BC and RCC in the 2000-2016 Surveillance, Epidemiology and End Results (SEER) database. We then reviewed our hospital records of patients with both BC and RCC and collected information including personal and family history of cancers, genetic testing, and patient outcomes.Results: Of the 813,477 females diagnosed with BC in the SEER database, 1,914 later developed RCC. The risk of developing RCC was significantly increased within the first six months, 7-12 months, and 1-5 years following BC diagnosis with standardized incidence ratios (SIRs) of 5.08 (95% CI, 4.62- 5.57), 2.09 (95% CI, 1.8-2.42), and 1.15 (95% CI, 1.06-1.24), respectively. Of 56,200 females with RCC, 1,087 later developed BC. The risk of developing BC following RCC was elevated within the first six months (SIR of 1.45 [95% CI, 1.20-1.73]). For our hospital patients, 437 had both BC and RCC. 427 (97.71%) were female, and 358 (81.92%) were white, and breast cancer was diagnosed before RCC in 246 (61.5%) patients. There were 15 germline mutations in those with genetic testing. Conclusion:Our findings suggest that BC patients are at higher risk of developing RCC and vice versa. BC tended to precede RCC, and patients frequently had personal histories of other malignancies and a family history of cancer, particularly BC.

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Synchronous invasive ductal carcinoma of the breast and clear cell renal carcinoma with rare presentation and behaviour: a case report with a literature review

Cited by 2 publications

References 12 publications

Studying the association between breast cancer and renal cell carcinoma

Studying the association between breast cancer and renal cell carcinoma

Studying the Association Between Breast Cancer and Renal Cell Carcinoma

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