Synchronous gastric adenocarcinoma and gastrointestinal stromal tumor (GIST) of the stomach: A case report

Theodosopoulos, Theodosios; Dellaportas, Dionysios; Psychogiou, V.; Gennatas, K; Kondi-Pafiti, Agathi; Gkiokas, Georgios; Papaconstantinou, Ioannis; Polymeneas, G.

doi:10.1186/1477-7819-9-60

Cited by 14 publications

(9 citation statements)

References 10 publications

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“…The presence of malignancies of two different cell lines in the same organ have been observed in clinical practice and published [1][2][3] It has been hypothesised that the carcinogenesis may be due to a single carcinogen acting under different milieux [1,3].…”

Section: Discussionmentioning

confidence: 99%

“…In the past, several cases of synchronous adenocarcinoma of stomach or small intestine and GIST have been reported in literatures worldwide [1,2,3]. In this particular case of interest, metastasis from operated adenocarcinoma of stomach is metachronously found metastasizing in a small bowel GIST.…”

Section: Introductionmentioning

confidence: 93%

“…In this particular case of interest, metastasis from operated adenocarcinoma of stomach is metachronously found metastasizing in a small bowel GIST. A hypothesis of gene mutation/deregulation can be put forth [2,3]. Proliferation of different cell lines induced by the same carcinogen at different points of time cannot be ruled out.…”

Section: Introductionmentioning

confidence: 99%

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The Burden of Respiratory Syncytial Virus Disease in Pre-Term Infants

Corsello

Carlo

2016

BJMMR

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Gastrointestinal stromal tumours (GIST) are rare mesenchymal neoplasms in the gastrointestinal tract. The metachronous existence of GIST and gastric adenocarcinoma, though are tumours of distinct histotype, and very rare, have been reported in medical case reports in recent years. We report a case of a 74 year old man who initially presented with moderately differentiated adenocarcinoma of the stomach, underwent Billroth 2 gastrectomy followed by chemotherapy. Subsequently, after 15 months he developed a GIST of small bowel with metastasis from adenocarcinoma of stomach. Taking into consideration the fact that metachronous occurrence of GIST of the gastrointestinal tract and adenocarcinoma of stomach is rare and further metastasis of one tumour into the other makes this case a rare one as per available literature.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 93%

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The Burden of Respiratory Syncytial Virus Disease in Pre-Term Infants

Corsello

Carlo

2016

BJMMR

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“…Past decades have witnessed frequent cases of synchronous occurrence of a GIST and another neoplasms [ 1 , 2 ]. However, gastric GISTs simultaneous development of a liposarcoma is rarely reported.…”

Section: Introductionmentioning

confidence: 99%

Coexistence of gastric gastrointestinal stromal tumor, intro-abdominal and retroperitoneal liposarcomas –a case report

Zhou¹,

Wang

Shi

et al. 2018

BMC Cancer

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BackgroundGastric gastrointestinal stromal tumor (GIST), intro-abdominal and retroperitoneal neoplasms are distinct tumors arising from different cell layers; therefore, coexistence of such tumors is relatively rare.Case presentationA man complained of early satiety for 2 mouths, whose upper gastrointestinal (GI) endoscopy showed a tumor arising from the greater curvature of gastric body and extending into the lumen. Abdominal computed tomography (CT) revealed coexistence of gastric, intro-abdominal and retroperitoneal masses. Wedge resection for gastric tumor, resection for intro-abdominal and retroperitoneal tumors were done. The postoperative histological examination suggested simultaneous development of a gastric GIST, intro-abdominal and retroperitoneal myxoid liposarcomas.ConclusionAlthough both GISTs and liposarcomas originate from mesenchymal tissues, simultaneous development of a gastric GIST, intro-abdominal and retroperitoneal liposarcomas is the first such case to be reported in the literature.

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“…Gastrointestinalstromal tumors (GIST) are rare mesenchymal tumors of the gastrointestinal tract with an incidence of 1,5/100000 habitant/year [ 1 ]. They occur in adults especially in the sixth an seventh decade [ 2 ].…”

Section: Introductionmentioning

confidence: 99%

Acute intestinal obstruction revealing synchronous gastrointestinal stromal tumors in a small bowel diverticulum and mucinous adenocarcinoma of the colon: a case report

Reda¹,

Jahid²,

Abderrahim³

et al. 2015

Pan Afr Med J

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Gastrointestinalstromal tumors are rare neoplasms and represent 0,1% to 3% of all gastrointestinal cancers. They are the most frequent mesenchymal neoplasms of the gastrointestinal tract with a malignant potential and unpredictable behavior. The synchronous association with other primary gastrointestinal carcinoma has been rarely reported in the literature with increasing number in the last ten years. The associated Gastrointestinalstromal tumor is usually discovered incidentally during surgery for carcinoma. The limited number of these cases cannot confirm the existence of a common factor in tumorigenesis of these different tumors and other studies are needed to clarify the possible association. We report the first case in the literature of synchronous primary Gastrointestinalstromal tumors developed in small bowel diverticulum and mucinous adenocarcinoma of the colon. Key words: Synchronous, Gastrointestinalstromal tumors, Adenocarcinoma, Colon.

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Synchronous gastric adenocarcinoma and gastrointestinal stromal tumor (GIST) of the stomach: A case report

Cited by 14 publications

References 10 publications

The Burden of Respiratory Syncytial Virus Disease in Pre-Term Infants

The Burden of Respiratory Syncytial Virus Disease in Pre-Term Infants

Coexistence of gastric gastrointestinal stromal tumor, intro-abdominal and retroperitoneal liposarcomas –a case report

Acute intestinal obstruction revealing synchronous gastrointestinal stromal tumors in a small bowel diverticulum and mucinous adenocarcinoma of the colon: a case report

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