Synchronous double cancers of the remnant stomach and pancreas: Report of a case

Abstract

We present here in the case of a 75-year-old man who developed synchronous double cancers of the remnant stomach and pancreas 12 years after undergoing distal gastrectomy for gastric carcinoma. The patient was referred to our hospital in March, 1993, with a provisional diagnosis of carcinoma of the remnant stomach. Laboratory data on admission showed an abnormal level of CA19-9 (116.1 U/ml) and positive occult blood in the stools. An upper gastrointestinal series and gastroendoscopy demonstrated an ulcerative polypoid tumor in the gastric stump proximal to the gastroduo-denostomy anastomosis, and a biopsy confirmed the findings of mucinous adenocarcinoma. Abdominal computed tomography (CT) scan revealed a low-density nodule anterior to the abdominal aorta, suggestive of a nodal metastasis. A laparotomy was performed which also disclosed a low-density mass located within the head of the pancreas. The patient was subsequently diagnosed as having double carcinomas of the remnant stomach and pancreas, and total gastrectomy and pancreatoduodenectomy were carried out. The histologic sections from the remnant stomach showed mucinous adenocarcinoma, whereas those from the pancreas showed tubular adenocarcinoma. Double carcinomas in this association are extremely rare and this case may in fact be the first observation of synchronous double cancers of the remnant stomach and pancreas.

Synchronous or metachronous double cancers of the pancreas and other organs: Report on 12 cases

“…However, reported cases of double cancer involving pancreatic cancer are relatively rare. [2][3][4] Nevertheless, according to Kamisawa et al, 5 pancreatic cancer was associated with a high incidence of malignancies of the gastrointestinal tract, especially the stomach. 6,7 The overall reported incidence of pancreatic cancer associated with other organ malignancies was 1.2%-20.0% (Table 3).…”

A Surgical Case of Synchronous Double Primary Cancers of the Bile Duct and Pancreas

“…The frequency of multiple primary tumors among all cases of malignancy ranges from 1-3%. 8 The frequency of pancreatic cancer in association with cancer of other organs is estimated to range from 7.3-16.7%. 9 According to the criteria presented by Warren and Gates, double cancers are defined as follows:…”

Diagnostic errors when interpreting abdominopelvic computed tomography: a pictorial review

“…In addition, synchronous primary cancers or multiple primary cancers are rare, having been reported in only 1-3% of malignancies. 6 It can be easy to miss cancer of another organ in the absence of an organized approach ( Figure 2). In cases of bowel perforation, coexisting malignancy could be overlooked because of a surrounding abscess or severe pericolic inflammation ( Figure 3).…”