Synchronous bilateral testicular seminoma in an adult patient with bilateral cryptorchidism: A case report and literature review

Morúa, Alejandro García; García, José Antonio Guevara; Gerardo, E. Ortiz Lara; Montelongo, Rafael Martínez; Lauro, S. Gómez Guerra

doi:10.1016/s2173-5786(10)70044-5

Cited by 3 publications

(1 citation statement)

References 11 publications

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“…However, 43 of these studies were excluded based on the inclusion and exclusion criteria. The remaining 51 studies included 39 in English [6,8–45], nine in Spanish [46–55], and one in Italian [56]. These studies encompassed a total of 938 men.…”

Section: Resultsmentioning

confidence: 99%

Bilateral testicular germ cell tumours: a systematic review

Zéqui¹,

Costa²,

Santana³

et al. 2012

BJU International

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What's known on the subject? and What does the study add? Bilateral testicular germ cell tumours (BTGCTs) are rare neoplasms. Most previously published studies consist of case reports or small retrospective case series. Little is known about their epidemiological and clinicopathological characteristics. BTGCT corresponded to 1.82% of testicular tumours. Metachronous disease was about twice as frequent as synchronous disease. The primary tumour histology, chemotherapy use and the interval between metachronous tumours influenced the histology of the second tumour. Overall, synchronous tumours were associated with more advanced disease and presented less favourable survival rates than metachronous tumours. Testicular cancer is the most common tumour in young men. It is known that a second primary contralateral testis tumour may occur in up to 5% of men with a proior tumour. About 35% of these men present with synchronous tumours, and 65% present with metachronous tumours. However there is little data about bilateral testicular germ cell tumours (BTGCT) in the literature and the most published articles are case reports on a small series of men, which makes it difficult to draw conclusions about therapeutic strategies for the treatment of BTGCTs. In fact, current guidelines for the treatment of testicular cancer contain little information related to bilateral disease. Therefore, the aim of our study is to provide a broad overview of BTGCT and to update data focusing on incidence, pathological features, and clinical outcomes of men with BTGCTs. Thus, an extensive review containing 94 studies and more than 50,000 patients was conducted.

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Section: Resultsmentioning

confidence: 99%

Bilateral testicular germ cell tumours: a systematic review

Zéqui¹,

Costa²,

Santana³

et al. 2012

BJU International

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Seminoma en testículo criptorquídico abdominal

Medina

Fernández-Aceñero

Daoud

et al. 2011

Revista Española de Patología

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Synchronous Seminoma in Abdominopelvic and Inguinal Testes: A Rare Presentation with Unusual Morphology

Prabhakar

Sethi

Nagger

et al. 2017

Case Reports in Pathology

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The development of testes occurs in the abdomen during fetal life, after which they migrate into the scrotal sacs during the third trimester. During their descent, they may get arrested anywhere along the tract. Risk of testicular cancer is higher in patients with undescended testes, abdominal testis being more prone than inguinal. Seminoma is the commonest cancer in undescended testis. However, synchronous seminoma involving bilateral cryptorchid testis is rare. Present case is uncommon due to synchronous involvement of abdominopelvic and inguinal testes in extended age. It also exhibited unusual morphology with marked heterogeneity grossly as well as microscopically, instead of a common homogenous appearance.

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Synchronous bilateral testicular seminoma in an adult patient with bilateral cryptorchidism: A case report and literature review

Cited by 3 publications

References 11 publications

Bilateral testicular germ cell tumours: a systematic review

Bilateral testicular germ cell tumours: a systematic review

Seminoma en testículo criptorquídico abdominal

Synchronous Seminoma in Abdominopelvic and Inguinal Testes: A Rare Presentation with Unusual Morphology

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