Synchronous activation within the default mode network correlates with perceived social support

Che, Xianwei; Zhao, Jing; Wei, Dongtao; Li, Bingbing; Guo, Yanan; Qiu, Jiang; Liu, Yijun

doi:10.1016/j.neuropsychologia.2014.07.035

Cited by 22 publications

(17 citation statements)

References 93 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Consistent with this, several previous studies measuring resting-state functional MRI reported functional connectivity between these regions (e.g., Gabard-Durnam et al, 2014;Veer et al, 2011). Future studies analyzing structural and/or functional networks associated with perceived social support (e.g., Che et al, 2014b) would be promising with regard to interest in the amygdala.…”

Section: Discussionsupporting

confidence: 81%

The association between perceived social support and amygdala structure

et al. 2016

View full text Add to dashboard Cite

The subjective perception of social support plays a crucial role in human well-being. However, its structural neural substrates remain unknown. We hypothesized that the amygdala, specifically its laterobasal and superficial subregions, which have been suggested to serve social functions, could be associated with the level of perceived social support. To test this hypothesis, we assessed perceived social support using the Multidimensional Scale of Perceived Social Support. In addition, we measured the volume and shape of the amygdala using structural magnetic resonance imaging in 49 healthy participants. Global amygdala volume in the left hemisphere was positively associated with the perceived social support score after adjusting for total cerebral volume, sex, age, intelligence, and five-factor personality domains. The local shape of the laterobasal and superficial subregions of the left amygdala showed the same association with perceived social support. These data suggest that the social subregions of the left amygdala are associated with the implementation of perceived social support.

show abstract

Section: Discussionsupporting

confidence: 81%

The association between perceived social support and amygdala structure

et al. 2016

View full text Add to dashboard Cite

show abstract

“…First, the present study included a small sample, which may have resulted in a lack of power for detecting associations between perceived social support and other www.nature.com/scientificreports www.nature.com/scientificreports/ brain regions. Our analyses using a liberal threshold revealed positive associations between MSPSS scores and fALFF values in several brain regions, including the precuneus, which is consistent with the results of a previous study 19 . The data suggest that more brain regions may be involved in the production of perceived social support.…”

Section: Discussionsupporting

confidence: 91%

Amygdala activity related to perceived social support

Sato

Kochiyama²,

Uono

et al. 2020

Sci Rep

View full text Add to dashboard Cite

Perceived social support enhances well-being and prevents stress-related ill-being. A recent structural neuroimaging study reported that the amygdala volume is positively associated with perceived social support. However, it remains unknown how neural activity in this region and functional connectivity (FC) between this and other regions are related to perceived social support. To investigate these issues, resting-state functional magnetic resonance imaging was performed to analyze the fractional amplitude of low-frequency fluctuation (fALFF). Perceived social support was evaluated using the Multidimensional Scale of Perceived Social Support (MSPSS). Lower fALFF values in the bilateral amygdalae were associated with higher MSPSS scores. Additionally, stronger FC between the left amygdala and right orbitofrontal cortex and between the left amygdala and bilateral precuneus were associated with higher MSPSS scores. The present findings suggest that reduced amygdala activity and heightened connectivity between the amygdala and other regions underlie perceived social support and its positive functions.The subjective perception of social support (i.e., the feeling of being supported by other people) plays a crucial role in human resilience and well-being. A number of psychological studies have shown that perceived social support prevents ill-being, such as perceived stress, anxiety, and depression 1-5 and enhances well-being, such as subjective happiness 6-9 . To investigate this important psychological construct, psychometric studies have developed several questionnaires, including the Multidimensional Scale of Perceived Social Support (MSPSS 10 ), that reliably and validly measure perceived social support. Subjectively perceived social support is related to received social support, but at only moderate strength, whereas it is more consistently linked to the aforementioned positive effects 11,12 . Based on these findings, it has been proposed that perceived social support is a stable characteristic, similar to a trait or a personality feature 11,13 .To explore the neural mechanisms underlying perceived social support, a recent structural neuroimaging study has investigated the regional brain volumes associated with perceived social support as measured using the MSPSS 14 . The study reported that left amygdala volume is positively associated with MSPSS scores, which indicates that the amygdala plays an important role in the implementation of perceived social support.However, the type of amygdala activity (i.e., hyper-or hypoactivity) related to perceived social support remains unknown. This information would be valuable for understanding the functional role of the amygdala in perceived social support. Several functional magnetic resonance imaging (fMRI) studies have indicated that low-frequency (<0.1 Hz) resting-state neural activity in the absence of a task is a suitable measure for assessing brain activity related to stable psychological constructs, such as perceived social support 15,16 . It has been proposed that t...

show abstract

“…Given their co-evolution with humans1917 and capabilities to respond to human cues17181956, they are an interesting species worth studying to investigate how similar traits may have arisen via evolution. One brain network that has been implicated in cognition in general (as well as in social cognition)5758 is the default mode network. The DMN is also known to underlie self-referential processing, consciousness, self-awareness and higher cognition in humans323738.…”

Section: Discussionmentioning

confidence: 99%

Characterization of Structural Connectivity of the Default Mode Network in Dogs using Diffusion Tensor Imaging

Robinson

Baxi

Katz

et al. 2016

Sci Rep

View full text Add to dashboard Cite

Diffusion tensor imaging (DTI) provides us an insight into the micro-architecture of white-matter tracts in the brain. This method has proved promising in understanding and investigating the neuronal tracts and structural connectivity between the brain regions in primates as well as rodents. The close evolutionary relationship between canines and humans may have spawned a unique bond in regard to social cognition rendering them useful as an animal model in translational research. In this study, we acquired diffusion data from anaesthetized dogs and created a DTI-based atlas for a canine model which could be used to investigate various white matter diseases. We illustrate the application of this atlas by calculating DTI tractography based structural connectivity between the anterior cingulate cortex (ACC) and posterior cingulate cortex (PCC) regions of the default mode network (DMN) in dogs. White matter connectivity was investigated to provide structural basis for the functional dissociation observed between the anterior and posterior parts of DMN. A comparison of the integrity of long range structural connections (such as in the DMN) between dogs and humans is likely to provide us with new perspectives on the neural basis of the evolution of cognitive functions.

show abstract

Synchronous activation within the default mode network correlates with perceived social support

Cited by 22 publications

References 93 publications

The association between perceived social support and amygdala structure

The association between perceived social support and amygdala structure

Amygdala activity related to perceived social support

Characterization of Structural Connectivity of the Default Mode Network in Dogs using Diffusion Tensor Imaging

Contact Info

Product

Resources

About