Synchronization of ovulation with human chorionic gonadotropin in lactating dairy cows with ovarian cysts during heat stress

Abstract

A study was conducted during hot season to determine the effect of synchronization of ovulation with human chorionic gonadotropin (hCG) on fertility of lactating dairy cows with ovarian cysts. Non cyclic Holstein dairy cows (n = 80) were stratified by parity and diagnosed as having an ovarian cyst. The cows were further identified as follicular or luteal cysts according to the plasma progesterone (P4) concentration and the cystic image of ultrasonography. Cystic cows were randomly assigned to receive treatments (Ovsynch as the control or Ovsynch plus 3000 IU hCG). All cows were artificially inseminated at 16-18 h after the second gonadotropin releasing hormone injection. Cows supplemented with hCG had a greater number of corpus luteum (1.8 ± 0.2 and 0.8 ± 0.3; P < 0.05) and had greater P4 concentration on day 12 than those control cows (6.3 ± 0.3 and 3.9 ± 0.4 ng/ml; P < 0.05). Concentration of cortisol did not differ between groups of cystic cows. No significant differences were found in overall conception rates between the treatments; however, significantly greater conception rate (P = 0.03) was observed in cows with luteal cysts receiving Ovsynch plus hCG. This study highlights that administration of hCG following the Ovsynch-based timed artificial insemination (AI) is more effective than the control Ovsynch by which the hCG affects corpus luteum (CL) development, P4 concentration, and thus improves conception rate in dairy cows with luteal cysts.

The presence of ovarian cysts in a captive Antillean manatee (Trichechus manatus manatus L. 1758)

“…Therefore, the detection of ovarian cysts in the described manatee was possible only after necropsy. The pathogenesis of the formation of ovarian cysts is well known in humans [ 30 , 31 ], cattle [ 32 – 34 ], pigs [ 35 ], cats [ 41 ] and dogs [ 39 , 40 ]. There is no available data regarding the formation of ovarian cysts in female manatees.…”

“…On the other hand, diet, living conditions, stress and age play a crucial role in the development of hormonal imbalance and, subsequently, lead to the formation of cysts or reproductive organ neoplasia. In cattle, the presence of ovarian cysts may cause behavioural disorders [ 28 , 33 , 34 ]. It is unclear whether such behavioural disturbances occur in marine mammals.…”

“…Studies on ovarian cysts are most commonly reported in humans [ 30 , 31 ], cattle [ 32 – 34 ], pigs [ 35 ], horses [ 36 ], goats [ 37 ], sheep [ 38 ], dogs [ 39 , 40 ], cats [ 41 ], guinea pigs [ 42 , 43 ], mice [ 44 , 45 ] and rhesus monkeys [ 46 ]. There have also been several reports of ovarian cysts in marine mammals, such as dugongs [ 47 ] and dolphins [ 48 ].…”

Estrus Performance and Pregnancy Rate in Types of Local Cows on Different Estrus Synchronization Protocols

“…The estrus ends approximately at the rupture of ovary follicle or at the start of ovulation (Hafez and Hafez, 2016). The duration of estrus in the combined PGF 2 α and hCG is because hCG does not directly affect the ovary (Navanukraw et al, 2015). Instead, the hormones produced by the hypothalamus stimulate the synthesis and release the follicle stimulating hormone (FSH) and luteinizing hormone (LH) from Anterior Pituitary (Araujo et al, 2009).…”

“…Akhtar et al (2013) suggests that hCG may increase the conception rates of buffaloes up to 100%. In addition, Navanukraw et al (2015) maintained that the administration of hCG in the synchronization of dairy cows was more effective in increasing pregnancy rates.…”