Symptoms, signs and complications in newly diagnosed type 2 diabetic patients, and their relationship to glycaemia, blood pressure and weight

Drivsholm, Thomas; Olivarius, Niels de Fine; Nielsen, Anni Brit Sternhagen; Siersma, Volkert

doi:10.1007/s00125-004-1625-y

Cited by 102 publications

(69 citation statements)

References 9 publications

(17 reference statements)

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“…Total 55 cases presented with sypmtoms classical for diabetes melltus like polyurea and polydipsia and increased appetite and was not associated with diabetic complications at the time of diagnosis. These findings are similar to the study done by Drivsholm et al [9] study. In our study we have found out CAD (n=42) 15.5%, Neuropathy (n =70) 25.9 % , Nephropathy (n=43) 15.5% .…”

Section: Discussionsupporting

confidence: 83%

Prevalence of Various Complications in Type II Diabetes Mellitus in Rural Medical College of Central India - A study

Tiwari¹,

Naagar²,

Kawre³

2015

JMSCR

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Section: Discussionsupporting

confidence: 83%

Prevalence of Various Complications in Type II Diabetes Mellitus in Rural Medical College of Central India - A study

Tiwari¹,

Naagar²,

Kawre³

2015

JMSCR

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“…In a study conducted in 1,137 Danish patients, a higher HbA1c level was associated with an increased frequency of balanitis in patients with diabetes compared with those without (OR 1.25, CI 1.09 to 1.44), despite adjustment for age, sex, body mass index, blood pressure, complications and antihypertensive treatment. 36 The inflammation, pain and discharge related to fungal balanitis may adversely affect sexual function. Peyronie's disease, which may be associated with sexual dysfunction, is more common in diabetes, with a higher incidence related to a longer duration of diabetes and poor glycaemic control.…”

Section: Diabetes and Other Sexual Dysfunctionsmentioning

confidence: 99%

Erectile dysfunction, diabetes and cardiovascular risk

Hackett

2016

Br J Diabetes

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Erectile dysfunction (ED) occurs in up to 75% of men with type 2 diabetes (T2DM) and has a complex pathogenesis owing to a combination of microvascular, macrovascular, endocrine and neuropathic disease. ED is established as an independent marker for the development of coronary artery disease (CAD) occurring on average 3 -5 years before the onset of CAD. Thus, timely detection of ED offers an opportunity for early intervention, thereby reducing morbidity associated with CAD. The average UK male, however, suffers for 3 years before discussing symptoms of ED with a healthcare professional. The National Institute for Health and Care Excellence (NICE) recommends an annual review of ED symptoms in susceptible patients with T2DM with an appropriate discussion of management options. Screening questions regarding ED were introduced in the 2013 Quality Outcome Framework but were removed by NHS England in 2014 on grounds of 'simplification'. Response to treatment strategies for ED is poor in diabetes, and poor glycaemic control, long duration of disease and severity of complications is predictive of a poor treatment response. The concomitant presence of hypogonadism in over 40% of men with T2DM also makes ED difficult to treat in this group. Further, ED and severe hypogonadism have been shown to independently predict mortality in T2DM. Treatment for ED is more likely to be effective if given early, although complex regimens may be required. Br J Diabetes 2016;16:52-57

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“…The diagnostic usefulness of the ADA symptoms may be limited by their occurrence in a restricted window of time between asymptomatic disease onset and treatment-induced symptom control. A recently published Danish study of newly diagnosed type 2 diabetic patients found that five of the seven ADA symptoms (frequent urination, abnormal thirst, weight loss, fatigue, and visual disturbances), plus symptoms of genital itching, stomatitis, confusion, and (in men) balanitis, were associated with glycemic level, irrespective of age, sex, BMI, blood pressure, antihypertensive treatment, or complications (11).…”

Section: Logistic Regressionmentioning

confidence: 99%

Symptoms of Diabetes and Their Association With the Risk and Presence of Diabetes

Clark

Fox²,

Grandy³

2007

Diabetes Care

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OBJECTIVE -The American Diabetes Association (ADA) lists seven symptoms of diabetes; however, it is not known how specific these symptoms are for initial diagnosis of type 2 diabetes. The Study to Help Improve Early evaluation and management of risk factors Leading to Diabetes (SHIELD) examined prevalence of ADA symptoms and their association with diabetes diagnosis. RESEARCH DESIGN AND METHODS-SHIELD is a 5-year observational study of individuals with or at risk for diabetes diagnosis. Following an initial screening phase, follow-up questionnaires were mailed to a stratified random sample of individuals (n ϭ 22,001) with type 1 or type 2 diabetes or at high (three to five risk factors) or low (zero to two risk factors) risk for diabetes. Individuals reported whether they experienced each ADA symptom, as well as symptoms unrelated to diabetes.RESULTS -A total of 15,794 questionnaires were returned (response rate 71.8%). All ADA symptoms were reported more frequently in type 2 diabetes than in low-and high-risk groups (P Ͻ 0.0001 for each). Multivariable logistic regression analyses found that each ADA symptom other than irritability was significantly associated with type 2 diabetes, as was erectile/sexual dysfunction. However, 48% of type 1 diabetic and 44% of type 2 diabetic respondents reported no ADA symptom in the previous year.CONCLUSIONS -Occurrence of ADA symptoms alone may not adequately identify those who should be evaluated for type 2 diabetes. Longitudinal data from SHIELD will evaluate whether combinations of symptoms or addition of other symptoms can better identify individuals for evaluation.

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Symptoms, signs and complications in newly diagnosed type 2 diabetic patients, and their relationship to glycaemia, blood pressure and weight

Cited by 102 publications

References 9 publications

Prevalence of Various Complications in Type II Diabetes Mellitus in Rural Medical College of Central India - A study

Prevalence of Various Complications in Type II Diabetes Mellitus in Rural Medical College of Central India - A study

Erectile dysfunction, diabetes and cardiovascular risk

Symptoms of Diabetes and Their Association With the Risk and Presence of Diabetes

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