Symptoms of Anxiety and Depression, and Quality of Life of Patients With Crohn’s Disease

Abstract

-Background -Crohn's disease is an idiopathic chronic inflammatory disease. It is classified as an inflammatory bowel disease. Crohn's disease can change patient quality of life, especially during flares. Crohn's disease has been associated with symptoms of anxiety and depression, because the clinical symptoms have a high impact on quality of life. Objective -To investigate the prevalence of symptoms of anxiety and depression in Brazilian patients diagnosed with Crohn's disease, as well as their quality of life. Methods -A total of 110 Brazilian patients aged 21-59 years, both genders, with Crohn's disease were included. The data were collected through questionnaires. The Hospital Anxiety and Depression Scale (HADS) was used to assess anxiety and depression symptoms. Quality of life was evaluated using the Inflammatory Bowel Disease Questionnaire. Data were analyzed by ANOVA, followed by the Duncan post-hoc test and the multiple linear regression test. Results -Of the total, 61.7% of participants reported symptoms of anxiety or depression or both. Regarding quality of life, the majority (43.6%) were classified as "regular" and the minority (3.6%) as "excellent". Multiple linear regression showed that worse quality of life correlated with greater presence of anxiety and depression symptoms (<0.001).Conclusion -Crohn's disease has considerable impact on quality of life and contributes to the appearance of anxiety and/or depression symptoms. HEADINGS -Crohn disease. Quality of life. Anxiety. Depression.

Quality of life and symptoms of anxiety and depression in patients affected by ulcerative colitis

“…The mean and standard deviation of the age of the participants in the present study was 31 ± 7.79, similar to other fi ndings in the literature, with mean ages of 21.2 years [6], 33 years [7] and 37.5 years [15]. Regarding marital status, the other studies [5,13,14] found that married people adhered better to treatment, representing at least 66% of the population, which is close to the result obtained herein.…”

“…The same peculiarity was described in the study by [11], who obtained similar results regarding the proportion of female individuals in their research, being three times higher when compared to the number of male individuals. Other studies [5,7,[12][13][14] also reported a greater participation of women in the analysis (> 50%). This is due to a greater concern with health and a greater endency to participate in health-related research that women mostly present [6], when carrying out a survey with 532 individuals diagnosed with CU, reported that 74.62% (n = 397) declared themselves to be white, similar to the present study.…”

“…The uncertain nature of the disease and its association with serious complications and the possible need for surgery or hospitalization to control symptoms render individuals with IBD more susceptible to develop anxiety or depression, especially during the stages of symptomatic intensifi cation of the disease [7,8]. According to the study by Freitas, et al…”

Quality of Life of Patients From a Multidisciplinary Clinic of Inflammatory Bowel Disease

“…IBD have a bimodal characteristic, with incidence in young adults and later in those over 50 years of age. The results of the study showed higher incidence in females (73.2%), CD diagnosis (63%), and an average age of patients 46.5 years, slightly above when compared with some studies (1)(2)(3)(4)(5)(6)(7)(8)(9) and the regional study of scores. These significant findings allow to establish the correlation between the two methods analyzed, being good indicators of QOL in patients with IBD.…”

“…Symptoms such as depressive mood, anxiety and irritability have a high impact on QOL and, according to Teixeira et al (11) , they may emerge as a response to real situations when faced with unpleasant facts. Benvegnú and Tomazoni (9) state that such symptomatology reflects psychological distress, and may exacerbate against the greater activity of the disease.…”