Quality of life and symptoms of anxiety and depression in patients affected by ulcerative colitis

Abstract

Introduction: Ulcerative Colitis (UC) is an Infl ammatory Bowel Disease (IBD) that can be divided into two periods: active and remission. Individuals affected by this pathology can manifest symptoms of anxiety and depression, as well as low quality of life, due to the symptomatology of this disease when active. Objective: Demonstrate the relationship between anxiety and depression with UC and its infl uence on quality of life. Material and methods: The present study involved 97 individuals affected with UC, who were assessed through the application of the HADS and IBDQ on the social network Facebook, as well as their individual feeds. The survey began after approval by the Research Ethics Committee of the Federal University of Fronteira Sul, upon obtaining informed consent from the patients. Results: The majority of the assisted participants was female, white, married, and residents of southwest Brazil. A prevalence of symptoms of anxiety and depression was observed in individuals with low quality of life and status of disease activity. Discussion: The results show that individuals who exhibited an active disease status presented a lower quality of life, anxiety, and depression.

Prevalence of anxiety and depressive symptoms in ulcerative colitis patients in Jordan and its relationship to patient-reported disease activity

“…We used patient-reported disease activity and did not measure disease activity using a biomarker, therefore, it is uncertain whether active disease reflected active symptoms due to inflammation or simply active symptoms associated with IBS. However, two thirds of all the patients in our study were females, and unlike other studies, there was no selection bias as all consecutive patients in the clinic agreed to join the study and were recruited 27 . The interviews with each patient were conducted in person and we used the most up-to-date parameters to evaluate patient PHQ-9 and GAD-7 scores.…”

The effects of spirulina (Arthrospira platensis) supplementation on anthropometric indices, blood pressure, sleep quality, mental health, fatigue status and quality of life in patients with ulcerative colitis: A randomised, double‐blinded, placebo‐controlled trial

“…2 Ulcerative colitis may lead to several additional problems, including, sudden weight loss, abdominal and joint pain, rectal pain and bleeding, cramping, constipation, frequent loose bowels, 3,4 severe fatigue, 5 poor sleep quality 6 and mental disorders. 7 However, the pathogenesis of this disease is not completely understood; indeed, several studies have documented that the interactions between genetic, environmental factors, gut microbiota and immunopathological responses are associated with the triggering of ulcerative colitis. [8][9][10][11] Typically, immunosuppressive and antiinflammatory drugs are used to control the immune-inflammatory reaction in ulcerative colitis patients 12 ; however, these drugs tend to cause a number of short-term or long-term side effects, such as incresesed risk of infection, hepatotoxicity, osteoporosis, tremor, eyes problems, gastrointestinal problems, pancreatitis, mental disorders and antigen-antibody reactions.…”