Symptom: Livedo

H, Rockl; Metz, J

doi:10.1007/978-3-642-81412-9_21

Cited by 2 publications

(2 citation statements)

References 14 publications

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“…Therefore livedo reticularis disappears after the skin is warmed, but livedo racemosa continues to persist or improves only slightly. Generalized racemose livedo (GRL) and cerebrovascular defects form a syndrome which is often linked to long-term intake of oral contraceptives, high nicotine intake and arterial hypertension (Rockl & Metz, 1979). Lubach and Stamm (1983) reported that 74",, of patients with GRL had transient or persistent neurological defects of the central nervous system, which usually arose several years after the onset of cutaneous symptoms.…”

Section: One Should Distinguish Between Livedo Reticularis Characterimentioning

confidence: 99%

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Generalized racemose livedo with cerebrovascular lesions (Sneddon syndrome): an occlusive arteriolopathy due to proliferation and migration of medial smooth muscle cells

Marsch

Muckelmann

1985

Br J Dermatol

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We describe two cases of livedo racemosa generalisata with cerebrovascular defects (Sneddon syndrome). The histology is characterized by a proliferation and migration of medial smooth muscle cells in ascending arterioles of the upper subcutis and deep dermis. Migrating smooth muscle cells with a high content of intermediate filaments colonize the sub-endothelial intimal space, with subsequent narrowing of the vessel lumen. Since the discoloration of the skin is provoked by a reactive dilatation of venules, the biopsy should be performed in the adjacent normal-looking skin, taking in the upper subcutis.

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Section: One Should Distinguish Between Livedo Reticularis Characterimentioning

confidence: 99%

“…IV.Ch.Marsch and R.Aiuckelmaiin a clear cytoplasm. Rockl and Metz (1979) maintain that these cells have an ultrastructural resemblance to smooth muscle cells, but no ultrastructural results have yet been published to clarify the exact nature ofthe cellular proliferation. PATIENTS Case /.…”

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confidence: 99%