This article discusses a mathematical model for the implementation of pharmacological products using Blockchain technology. In addition, the current problems of the shadow drug market (corruption, resale) are analyzed and practical solutions are given to eliminate them. Blockchain technology, due to its decentralization, is one of the best solutions today. This is due to confidentiality, the immutability of the hash function, the speed of transactions within the technology. The integration of the hybrid Blockchain will allow using distributed registries more deeply -entering data into the Blockchain about transportation, about the conditions of logistics activities, about expiration dates, etc. Tracking can be done using marking matrix codes (Data Matrix), which are now implemented by the Information Monitoring System drug movement. The operator is the Center for the Development of Advanced Technologies (CDAT), which is already using Blockchain technologies to compile marking codes. In addition, the article presents a schematic representation of the industrial sale of medicines using Blockchain technology. The strengths of its introduction into the sales structure are shown. All this distinguishes Blockchain technology from other current trends.