Switching from subcutaneous to sublingual immunotherapy during the maintenance phase in patients with house dust mite allergy

Kiatiwat, Ploykarn; Sangasapaviliya, Atik; Pradubpongsa, Panitan; Sangkanjanavanich, Sasipa; Chiewchalermsri, Chirawat; Jacquet, Alain; Jaisupa, Nattapol; Jindarat, Sarawut; Boonpiyathad, Tadech; Mitthamsiri, Wat

doi:10.1111/all.15669

Cited by 1 publication

(2 citation statements)

References 10 publications

(15 reference statements)

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“…Allergen immunotherapy aims to reprogram the immune system through repeated administration of the causative allergen in a controlled manner 62 . AIT is indicated for patients with AR whose symptoms remain uncontrolled by avoidance and pharmacotherapy 2 .…”

Section: Treatment Strategies For Armentioning

confidence: 99%

“…Allergen immunotherapy aims to reprogram the immune system through repeated administration of the causative allergen in a controlled manner. 62 AIT is indicated for patients with AR whose symptoms remain uncontrolled by avoidance and pharmacotherapy. 2 AIT can be applied subcutaneously (SCIT) or sublingually (SLIT) and is suitable for children and adults for a variety of allergens, including pollen, cat, dog, house dust mite, and venom.…”

Section: Aitmentioning

confidence: 99%

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Immunomodulatory properties of mesenchymal stem cells: A potential therapeutic strategy for allergic rhinitis

Wang

Zhao

Zhang

2023

Allergy

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Allergic rhinitis (AR) is a common inflammatory disorder in the nasal mucosa caused by a hyperresponse of the immune system to allergens. The clinical symptoms of AR include sneezing, nasal discharge, itching, and congestion, which have a great impact on health-related quality of life. Since the 1960s, the global prevalence of AR has steadily increased. 1 Currently, the estimated prevalence of AR is 5%-15% in children and 10%-40% in adults. 2,3 The prevalence of allergen-specific immunoglobulin E (IgE) (to any allergen) has been estimated to exceed 50% of the population in Westernised countries. 1 Currently, pharmacotherapy is the cornerstone intervention for AR. However, while this method can control symptoms, it cannot reverse the state of immune imbalance of AR. Moreover, guidelinedirected pharmacotherapy is ineffective for up to 20% of people with AR. 4 Therefore, new and effective treatments are required.

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Section: Treatment Strategies For Armentioning

confidence: 99%

Section: Aitmentioning

confidence: 99%