Swertia chirayita: A comprehensive review on traditional uses, phytochemistry, quality assessment and pharmacology

Swertia L., as a commonly used ethnic medicine, is widely distributed in Sichuan, Yunnan, and Xizang in China. Moreover, the medicinal plants of Swertia L. have been widely used and constitute one of the most important sources of various traditional medicines in China due to their prominent activities. In this review, the information on the classification, distribution, genetic relationship, chemical composition, pharmacological effects, toxicities, and applications of the medicinal plants in Swertia L. was summarized based on the scientific literature. The results indicated that the medicinal plants of Swertia L. mainly contained chemical components including triterpenes, xanthones, and iridoids. These compounds exert pharmacological effects including ameliorating diseases related to the liver and gallbladder. They also exert antiviral and antibacterial effects and can alleviate the increase in blood glucose levels. Especially, prescriptions related to Swertia L. have been widely adopted in preclinical and clinical studies to protect against diseases affecting the liver and the gallbladder, including hepatitis, cirrhosis, and cholecystitis. In addition, it also discusses toxicity studies and future perspectives and provides a reference for their clinical development and utilization.

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Swertia L.: A comprehensive review of its genetic relationship, chemical compositions, pharmacological effects, toxicities, and applications

Guo

Xing

et al. 2023

Phytotherapy Research

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Versatile Therapeutic Potential of Swertia chirayita (Roxb.) H. Karst: A Review

Verma,

Pundir,

Goyal

et al. 2024

Chemistry Africa

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Deciphering the healing power of Swertia Chirayita: A potential treatment for acute liver injury

Guo,

Wu,

Liu

et al. 2024

Arabian Journal of Chemistry

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Swertia chirayita: A comprehensive review on traditional uses, phytochemistry, quality assessment and pharmacology

Cited by 6 publications

References 126 publications

Swertia L.: A comprehensive review of its genetic relationship, chemical compositions, pharmacological effects, toxicities, and applications

Swertia L.: A comprehensive review of its genetic relationship, chemical compositions, pharmacological effects, toxicities, and applications

Versatile Therapeutic Potential of Swertia chirayita (Roxb.) H. Karst: A Review

Deciphering the healing power of Swertia Chirayita: A potential treatment for acute liver injury

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